Predicting In-Hospital Mortality in Elderly Patients With Cervical Spine Fractures: A Comparison of the Charlson and Elixhauser Comorbidity Measures

Spine
Mariano E MenendezThomas D Cha

Abstract

Retrospective analysis of nationally representative data collected for the National Hospital Discharge Survey. To compare the performance of the Charlson and Elixhauser comorbidity-based measures for predicting in-hospital mortality after cervical spine fractures. Mortality occurring as a consequence of cervical spine fractures is very high in the elderly. The Charlson comorbidity measure has been associated with an increased risk of mortality, but its predictive accuracy has yet to be compared with the more recent and increasingly used Elixhauser measure. Using the National Hospital Discharge Survey for the years 1990 through 2007, we identified all patients aged 65 years or older hospitalized with a diagnosis of cervical spine fracture. The association of each Charlson and Elixhauser comorbidity with mortality was assessed in bivariate analysis using χ tests. Two main multivariable logistic regression models were constructed, with in-hospital mortality as the dependent variable and 1 of the 2 comorbidity-based measures (as well as age, sex, and year of admission) as independent variables. A base model that included only age, sex, and year of admission was also evaluated. The discriminative ability of the models was quantified...Continue Reading

References

Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
Nov 1, 1994·Environmental Health Perspectives·A N TostesonC B Begg
Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Sep 15, 2001·Journal of General Internal Medicine·W A GhaliR Brant
Oct 30, 2001·American Journal of Epidemiology·S SchneeweissR J Glynn
Apr 10, 2002·The Journal of Bone and Joint Surgery. American Volume·Timothy BhattacharyyaWilliam L Healy
Sep 13, 2003·Health Services Research·Sebastian SchneeweissRobert J Glynn
Feb 3, 2007·The Journal of Bone and Joint Surgery. American Volume·Alan H DanielsRobert A Hart
Aug 16, 2008·Clinical Orthopaedics and Related Research·Stavros G MemtsoudisThomas P Sculco
Dec 17, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Robert P MyersGilaad G Kaplan
Mar 3, 2010·The Journal of Bone and Joint Surgery. American Volume·Mitchel B HarrisJeffrey N Katz
Apr 21, 2010·The Journal of Trauma·John R DimarLeah Y Carreon
Jan 7, 2011·Journal of Clinical Epidemiology·Joshua J GagneSebastian Schneeweiss
Jun 10, 2011·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Hossein PakzadEugene K Wai
Aug 30, 2012·Medical Care·Mansour T A SharabianiAlex Bottle
Nov 28, 2012·Clinical Orthopaedics and Related Research·Valentin NeuhausDavid C Ring
Jul 31, 2013·The Journal of Arthroplasty·James A BrowneWendy M Novicoff
Sep 26, 2013·Gastrointestinal Endoscopy·Udayakumar NavaneethanMadhusudhan R Sanaka
Oct 30, 2013·Clinical Orthopaedics and Related Research·Kushal V PatelMatthew L Davis
Jan 21, 2014·Journal of Clinical Gastroenterology·Amnon Sonnenberg
Feb 12, 2014·The American Journal of Emergency Medicine·Peter W GreenwaldNeal Flomenbaum
Mar 4, 2014·Foot & Ankle International·Mariano E MenendezA Holly Johnson
Apr 16, 2014·Spine·Hiroyuki Yoshihara, Daisuke Yoneoka
May 29, 2014·Clinical Orthopaedics and Related Research·Mariano E MenendezDavid Ring

❮ Previous
Next ❯

Citations

May 18, 2016·Journal of Vascular Surgery·Kate P ZimmermanRandall R DeMartino
Jul 24, 2018·The Journal of Trauma and Acute Care Surgery·Robert S GreenMete Erdogan
Sep 21, 2017·The Journal of Trauma and Acute Care Surgery·Chao WenYa-Yang Liu
Jun 7, 2019·BMC Medical Research Methodology·David MetcalfeMatthew Costa
Feb 14, 2019·PM & R : the Journal of Injury, Function, and Rehabilitation·Conan SoJeffrey C Schneider
Nov 28, 2020·Internal and Emergency Medicine·Joshua BaxterThang Sieu Han
Feb 27, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·C Y BarreyY P Charles
Jun 3, 2020·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Pei-Ling TangChien-Jen Hsu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.