Predicting mortality of patients hospitalized for acutely exacerbated chronic obstructive pulmonary disease

The American Journal of Medicine
L FusoG Ciappi

Abstract

To identify factors affecting the short-term prognosis of patients with acutely exacerbated chronic obstructive pulmonary disease (COPD). The 590 patients having COPD as primary disease who were hospitalized in the pneumology unit of a university hospital from 1981 to 1990 were studied. A standardized protocol for the treatment of acutely exacerbated COPD was adopted for all the patients. The patient records were retrospectively analyzed by two observers, and 23 clinical and laboratory variables defining the patient status on admission were collected. Age and arterial gas data were also taken into account, and the outcome mortality was recorded. Interobserver reproducibility was tested by computing the kappa coefficient and Spearman's rho for dichotomous and continuous variables, respectively. The relationship of clinical and laboratory factors to the outcome was assessed first by univariate analysis and then by a logistic regression analysis assessing the independent predictive role of variables previously shown to be univariately correlated with mortality. The mortality rate was 14.4%. The logistic regression analysis identified four independent predictors of death: age (odds ratio [OR] 1.07; 95% confidence interval [CI] 1.04...Continue Reading

References

Jan 1, 1992·Journal of the American Geriatrics Society·A R IncalziP Carbonin
Sep 1, 1989·The American Review of Respiratory Disease·N R Anthonisen
Sep 1, 1989·The American Review of Respiratory Disease·J ManfredaW Litven
Sep 1, 1989·The American Review of Respiratory Disease·F E SpeizerB G Ferris
Jan 1, 1972·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·K L Raheja, J G Snedecor
Jan 1, 1980·Annual Review of Physiology·P D Wagner
Oct 1, 1982·The Journal of Clinical Endocrinology and Metabolism·J Kleinbaum, H Shamoon

Citations

Apr 24, 2013·Annals of the American Thoracic Society·Aran SinganayagamJames D Chalmers
Nov 5, 2013·European Journal of Internal Medicine·R A IncalziClaudio Pedone
Nov 27, 2007·European Journal of Epidemiology·Cynthia de LuiseHenrik Toft Sørensen
Apr 9, 2001·Aging : Clinical and Experimental Research·R A IncalziGIFA. Gruppo Italiano di Farmacovigilanza (Italian Group for Pharmacological Survey in the Elderly)
Jul 28, 2010·QJM : Monthly Journal of the Association of Physicians·J SteerS C Bourke
Dec 31, 2010·International Journal of Chronic Obstructive Pulmonary Disease·Martine HoogendoornMaureen Rutten-van Mölken
Sep 22, 2011·ClinicoEconomics and Outcomes Research : CEOR·Sevket OzkayaAtilla Guven Atici
Mar 7, 2012·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ilker Murat CaglarGokhan Ozmen
Apr 5, 2013·Multidisciplinary Respiratory Medicine·Giorgio FumagalliClaudio Maria Sanguinetti
May 11, 2004·Aging Clinical and Experimental Research·Raffaele Antonelli Incalzi
Oct 6, 2012·Respiration; International Review of Thoracic Diseases·R H J SlenterG G U Rohde
Oct 22, 2008·Journal of Clinical and Experimental Neuropsychology·Raffaele Antonelli-IncalziFranco Rengo
Nov 23, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Chu-Lin TsaiCarlos A Camargo
Jun 21, 2002·Journal of Internal Medicine·R A IncalziP Carbonin
Jul 26, 2006·American Journal of Respiratory and Critical Care Medicine·Noriaki TakabatakeIsao Kubota
Oct 9, 2009·COPD·David Halpin, Donald P Tashkin
Dec 7, 2006·COPD·Markus O HenkeBruce K Rubin
Jan 20, 2016·The Lancet. Respiratory Medicine·Martin I MacDonaldRobert J Hancox
May 18, 2013·Chest·Niyada NaksukSelcuk Adabag
Nov 24, 2005·Chest·Johnson GeorgeKay Stewart
Aug 17, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Martine HoogendoornMaureen P M H Rutten-van Mölken
Jul 29, 2015·International Journal of Cardiology·Christos A GoudisPanagiotis Korantzopoulos
Jun 16, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·Qiuyue Wang, Jean Bourbeau
May 12, 2006·Journal of the American Geriatrics Society·R A IncalziVincenzo Bellia
Jan 20, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Simone Scarlata, Raffaele Antonelli-Incalzi
Oct 2, 2007·The American Journal of Medicine·Andrea CorsonelloR A Incalzi
Feb 18, 2003·Intensive Care Medicine·Christophe BaillardLaurent Brochard
Mar 18, 2003·Intensive Care Medicine·Sean P KeenanJohn J Spinelli
May 4, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J Mensa, A Trilla
Dec 14, 2005·Pulmonary Pharmacology & Therapeutics·Claudio F Donner
Jan 19, 1999·Critical Care Clinics·S JainK K Guntupalli
Apr 24, 2001·Clinics in Chest Medicine·M L Nevins, S K Epstein
Feb 24, 2001·Clinics in Chest Medicine·J M Sethi, M D Siegel
Jul 15, 2015·Progress in Cardiovascular Diseases·Azfar SheikhHakan Paydak
Jul 16, 2013·COPD·Sheena Xin LiuDavid P White
Apr 30, 2015·European Heart Journal·Lies LahousseGuy G Brusselle
Jun 12, 2010·Respiratory Medicine·Stephen A MurphyGeorge Antunes
Feb 6, 2013·International Journal of Cardiology·Jocasta BallSimon Stewart
Oct 26, 2010·Respiratory Medicine·Mary GeitonaDemosthenes Bouros
May 19, 2012·Respiratory Medicine·Surya P BhattJohn S Kintzer
Dec 23, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Agence Française de Sécurité Sanitaire des Produits de Santé
Sep 19, 2016·Revue des maladies respiratoires·L SakhriA-C Toffart
May 21, 2011·Chronic Respiratory Disease·Nabil Jarad
Apr 5, 2008·Angiology·Leo MoroRaffaele Antonelli-Incalzi
Jul 21, 2009·Therapeutic Advances in Respiratory Disease·Antonio Anzueto, Marc Miravitlles
Mar 9, 2012·Respiration; International Review of Thoracic Diseases·Raffaele Antonelli-Incalzi
Jun 20, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Wei-Syun Hu, Cheng-Li Lin
Oct 13, 2018·Journal of Clinical Pharmacy and Therapeutics·Cameron D ThomasJason A Ferreira
Apr 9, 2005·Southern Medical Journal·Fernando de la IglesiaFernando Diz-Lois
May 8, 2008·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Killen Harold Briones ClaudettGumersindo Gonzalez Diaz
Aug 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Marc Miravitlles
Jan 11, 2012·Current Opinion in Pulmonary Medicine·Andrea CorsonelloFabrizia Lattanzio
Feb 26, 2020·Expert Review of Respiratory Medicine·Mutlu Kuluöztürk, Figen Deveci
Jul 20, 2004·Intensive Care Medicine·Raffaele ScalaMark W Elliott
Aug 18, 2020·Aging Clinical and Experimental Research·Alessia FumagalliDaniele Colombo
Mar 5, 2016·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·C A BuzeaG A Dan
Jun 25, 2005·British Journal of Nursing : BJN·Sue Cross
Jul 15, 2018·BMC Pulmonary Medicine·Domenico AcanforaMarco Matteo Ciccone
Aug 18, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Bojidar A RangelovJohn R Hurst
Mar 14, 2003·The Medical Journal of Australia·David K McKenzieThoracic Society of Australia and New Zealand
Nov 6, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Andriana I PapaioannouNikos Tzanakis
Feb 2, 2021·Journal of Diabetes and Metabolic Disorders·Sorur JavanmardifardFatemeh Shirazi
Dec 1, 2010·Journal of Chemotherapy·F BlasiGIARIR
Dec 10, 2019·Chest·Xiaochun XiaoJia He
May 1, 2021·Thorax·Eleanor L AxsonJennifer K Quint

Related Concepts

Acute Disease
Blood Gas Analysis
Decision Trees
Hospitalization
Lung Diseases, Obstructive
Relapse
Retrospective Studies
Reproducibility of Results
Intraobserver Variation
Logistic Regression

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