Oct 22, 1977

Predicting patients' warfarin requirements

P A RoutledgeM D Rawlins


In 34 patients undergoing anticoagulant therapy with warfarin a close relationship has been observed between the logarithm of the 'Thrombotest' response to a loading dose (10 mg/day for three days) and the maintenance dose required to achieve an anticoagulant response of 8-12% (thrombo-test). This relationship appears to be close enough to enable maintenance dosages to be predicted.

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Mentioned in this Paper

Mitral Valve
Crescendo Transient Ischemic Attacks
Blood Coagulation
Heart Valve Disease
Phlegmasia Alba Dolens
Anti-coagulant [EPC]
Dose-Response Relationship, Drug

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