Predicting phototoxicity of alkylated PAHs, mixtures of PAHs, and water accommodated fractions (WAF) of neat and weathered petroleum with the phototoxic target lipid model

Environmental Toxicology and Chemistry
Solmaz MarzooghiDominic M Di Toro

Abstract

The toxicity of petroleum can increase considerably after exposure to solar radiation, during which certain components in the mixture, including polycyclic aromatic hydrocarbons (PAHs), absorb light in ultraviolet and visible portions of the solar radiation spectrum. A phototoxic target lipid model (PTLM), previously developed to predict the phototoxicity of single PAHs, is validated for 4 species (Americamysis bahia, Rhepoxynius abronius, Daphnia magna, and Pimephales promelas) exposed to 12 compounds that are components of petroleum, including alkylated PAHs and dibenzothiophene. The PTLM is also used to predict the phototoxicity of binary and ternary mixtures of 3 PAHs, pyrene, anthracene, and fluoranthene, to A. bahia and Menidia beryllina. Finally, it is used to predict the toxicity of water accommodated fractions of neat and naturally weathered Macondo crude oil samples from the Deepwater Horizon oil spill sites. The Gulf of Mexico species, including A. bahia, M. beryllina, Cyprinodon variegatus, and Fundulus grandis were exposed to the oil samples under natural and simulated solar radiation. The results support the applicability of the PTLM for predicting the phototoxicity of petroleum. Environ Toxicol Chem 2018;37:2165-...Continue Reading

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Aug 24, 2016·Environmental Toxicology and Chemistry·Solmaz MarzooghiDominic M Di Toro
Oct 30, 2016·Environmental Toxicology and Chemistry·Aaron D RedmanThomas F Parkerton
Dec 25, 2016·Environmental Toxicology and Chemistry·Solmaz Marzooghi, Dominic M Di Toro
Apr 19, 2017·Environmental Toxicology and Chemistry·Bryson E FinchWilliam A Stubblefield

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Citations

Apr 25, 2020·The Science of the Total Environment·F Mikaela NordborgAndrew P Negri
Mar 16, 2021·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·R E NealeM Zhu

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