Predicting postoperative complications of inguinal lymph node dissection for penile cancer in an international multicentre cohort

BJU International
Jared M GopmanPhilippe E Spiess

Abstract

To assess the potential complications associated with inguinal lymph node dissection (ILND) across international tertiary care referral centres, and to determine the prognostic factors that best predict the development of these complications. A retrospective chart review was conducted across four international cancer centres. The study population of 327 patients underwent diagnostic/therapeutic ILND. The endpoint was the overall incidence of complications and their respective severity (major/minor). The Clavien-Dindo classification system was used to standardize the reporting of complications. A total of 181 patients (55.4%) had a postoperative complication, with minor complications in 119 cases (65.7%) and major in 62 (34.3%). The total number of lymph nodes removed was an independent predictor of experiencing any complication, while the median number of lymph nodes removed was an independent predictor of major complications. The American Joint Committee on Cancer stage was an independent predictor of all wound infections, while the patient's age, ILND with Sartorius flap transposition, and surgery performed before the year 2008 were independent predictors of major wound infections. This is the largest report of complication r...Continue Reading

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Citations

Jan 24, 2016·Urology·Gregory J DiorioPhilippe E Spiess
Jul 24, 2015·BJU International·Christian P MeyerJesse D Sammon
Oct 9, 2016·The Urologic Clinics of North America·Pranav SharmaPhilippe E Spiess
Apr 13, 2017·Nature Reviews. Urology·Andrew LeonePhilippe E Spiess
Mar 21, 2017·BJU International·Nick Watkin
Jan 3, 2019·Current Opinion in Urology·Reza Nabavizadeh, Viraj Master
Feb 8, 2019·Current Opinion in Urology·Juan ChipolliniPhilippe E Spiess
Sep 25, 2017·Current Opinion in Urology·Sarah R OttenhofErik Vegt
Aug 7, 2020·Journal of Clinical Medicine·Reza NabavizadehViraj Master
Jan 25, 2017·The Journal of Urology·Jonathan S O'BrienNathan Lawrentschuk
Nov 15, 2016·Cancer Control : Journal of the Moffitt Cancer Center·Pranav SharmaPhilippe E Spiess
May 10, 2019·F1000Research·Maximilian J Johnston, Raj Nigam
Nov 25, 2020·Current Treatment Options in Oncology·Mohamed E AhmedPhilippe E Spiess
Feb 12, 2021·Scandinavian Journal of Urology·Jakob Kristian JakobsenJørgen Bjerggaard Jensen
Aug 10, 2021·Emergency Medicine International·Demis N LipeMonica K Wattana

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