Abstract
Previous studies have demonstrated that patients with traumatic brain injury (TBI) who also have progressive hemorrhagic injury (PHI), have a higher risk of clinical deterioration and worse outcomes than do TBI patients without PHI. Therefore, the early prediction of PHI occurrence is useful to evaluate the status of patients with TBI and to improve outcomes. The objective of this study was to develop and validate a prognostic model that uses information available at admission to determine the likelihood of PHI after TBI. Retrospectively collected data were used to develop a PHI prognostic model with a logistic regression analysis. The prediction model was validated in 114 patients from a separate hospital. Eight independent prognostic factors were identified: age ≥ 57 years (5 points), intra-axial bleeding/brain contusion (4 points), midline shift ≥ 5 mm (6 points), platelet (PLT) count<100×10⁹/L (10 points), PLT count ≥ 100 but <150×10⁹/L (4 points), prothrombin time>14 sec (7 points), D-dimer ≥ 5 mg/L (12 points), and glucose ≥ 10 mmol/L (10 points). Each patient was assigned a number of points proportional to the regression coefficient. We calculated risk scores for each patient and defined three risk groups: low risk (0-13...Continue Reading
References
Feb 1, 1992·Neurosurgery·S C SteinS E Ross
Jan 1, 1993·Neurosurgery·S C SteinS E Ross
May 1, 1997·Journal of Neurosurgery·H TakahashiA Takada
Jan 17, 2002·Journal of Neurosurgery·Matthias OertelNeil A Martin
Feb 18, 2005·Journal of Neurotrauma·Martin EngströmPeter Reinstrup
Mar 29, 2005·Neurosurgery·Arturo ChieregatoFranco Servadei
Apr 1, 2006·Neurosurgery·Edward F ChangMartin C Holland
Feb 27, 2007·Stroke; a Journal of Cerebral Circulation·Ryan WadaSean P Symons
May 22, 2007·Journal of Neurotrauma·Susan L BrattonDavid W Wright
May 22, 2008·Journal of Neurotrauma·Raj K NarayanUNKNOWN Traumatic Intracerebral Hemorrhage Study Group
Jan 10, 2009·The Journal of Trauma·Deborah M SteinThomas M Scalea
Nov 11, 2009·The Journal of Trauma·Christopher B AllardSandro B Rizoli
Feb 5, 2010·Neuroradiology·Wu-Song TongHui Yu
Mar 30, 2010·Neurosurgical Review·Heng-Li TianShi-Wen Chen
Apr 14, 2010·The Journal of Trauma·Beat SchnürigerDemetrios Demetriades
Jan 20, 2011·Neurosurgical Review·Marc A SeifmanPeter Y K Hwang
Citations
Jun 7, 2014·Peptides·Ding-Bo YangYuan-Feng Du
Feb 7, 2016·Journal of Neurotrauma·Qiang YuanJin Hu
Oct 13, 2015·BioMed Research International·Danfeng ZhangLijun Hou
Jan 6, 2015·Journal of Neurotrauma·Hoon KimKwang Wook Jo
Sep 11, 2013·PloS One·Dawei DaiHengli Tian
Jul 31, 2016·Neurocritical Care·Randall Z AllisonMatthew A Koenig
Dec 19, 2017·Frontiers in Neurology·Guangfu DiHongyi Liu
Jan 6, 2018·Journal of Neurosurgery·Joseph A CarnevaleWael F Asaad
Aug 28, 2014·The Journal of Trauma and Acute Care Surgery·Bellal JosephPeter Rhee
Jul 8, 2020·PloS One·Isabella Vargas BaldonMarcos Rosa-Júnior
Dec 13, 2016·Acta neurochirurgica·Xueyan WanTing Lei
May 29, 2020·Neurocritical Care·Krishma AdatiaDavid K Menon
Oct 6, 2020·Frontiers in Neuroscience·Hao ChenLixia Xue
Jan 13, 2018·Journal of Neurotrauma·Carl MarincowitzTrevor A Sheldon
Jan 16, 2020·International Journal of Molecular Sciences·Ruchira M JhaJ Marc Simard
Apr 10, 2017·Metabolic Brain Disease·Hao ChenHeng-Li Tian
Aug 5, 2018·Medicine·Jing ZhangJianguo Xu
Dec 5, 2019·Neurocritical Care·Pierre EsnaultEric Meaudre
Aug 31, 2020·Curēus·Michael KarsyWilliam Couldwell
Oct 28, 2020·Journal of Neurotrauma·David RobinsonNatalie Kreitzer
Nov 19, 2020·Journal of Neurotrauma·Ruchira M JhaPatrick M Kochanek
Aug 7, 2019·Journal of Neurotrauma·Kelly A FairSusan E Rowell
Apr 22, 2021·Chinese Neurosurgical Journal·Wenxing CuiYan Qu
Jun 12, 2021·Frontiers in Neurology·Zhiji TangQiuhua Jiang
Jul 27, 2021·JAMA Network Open·Ruchira M JhaPatrick M Kochanek