Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception

Rheumatology
Michael HughesAriane L Herrick

Abstract

To evaluate whether patients can predict attacks of RP (if so, this would have implications for developing new treatments) and to evaluate the impact of RP attacks on quality of life (QoL). Individuals with RP were invited through international patient associations to participate in an online survey. Responses from 443 subjects with self-reported RP from 15 countries were evaluable. The mean age of subjects was 41 years (91% female). Fifty-eight per cent of subjects reported they could predict at least 51% of RP attacks, and 57% could predict attack severity either fairly well or better [with 43% predicting severity only poorly (30%) or very poorly (13%)]. Sixty-four per cent of subjects reported a poor or very poor current ability to prevent/control RP attacks. One hundred and eighty-two subjects (41%) reported current or previous use of medications for RP: 82% reported at least one currently used medication being tolerated, but only 16% reported at least one current medication being effective. Most subjects (78%) reported making at least one life adjustment due to RP, with more in subjects with secondary RP compared with primary RP (87% vs 71%, P = 0.001). Current QoL with RP was impaired [mean = 6/10 (10 best imaginable)] an...Continue Reading

References

Sep 27, 2002·The New England Journal of Medicine·Fredrick M Wigley
Oct 2, 2002·Arthritis and Rheumatism·Peter A MerkelUNKNOWN Scleroderma Clinical Trials Consortium
Sep 4, 2008·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Rossella De AngelisWalter Grassi
Jul 12, 2012·Nature Reviews. Rheumatology·Ariane L Herrick
May 15, 2013·Arthritis and Rheumatism·Marco Matucci-CerinicFredrick M Wigley

❮ Previous
Next ❯

Citations

Jan 24, 2016·Autoimmunity Reviews·Anne Claire Desbois, Patrice Cacoub
May 3, 2016·Seminars in Arthritis and Rheumatism·Camelia FrantzYannick Allanore
Aug 11, 2016·The New England Journal of Medicine·Fredrick M Wigley, Nicholas A Flavahan
Oct 22, 2016·Seminars in Arthritis and Rheumatism·Tien TayUNKNOWN Damage Index Working Group of the Scleroderma Clinical Trials Consortium
Jan 17, 2017·Expert Review of Clinical Immunology·Ariane L Herrick
Dec 5, 2017·Therapeutic Advances in Musculoskeletal Disease·Ariane L Herrick
Sep 10, 2019·British Journal of Hospital Medicine·Michael Hughes, Ariane L Herrick
Aug 20, 2019·Clinical Rheumatology·John D PaulingJanet E Pope
Aug 20, 2016·Current Opinion in Rheumatology·Ariane L Herrick
Feb 26, 2016·The Cochrane Database of Systematic Reviews·Holly EnnisAriane L Herrick
Feb 27, 2020·Nature Reviews. Rheumatology·Michael HughesMarco Matucci-Cerinic
Jul 17, 2020·Dermatologic Therapy·Yuanzhuo WangQiuning Sun
Mar 15, 2018·Rheumatology·John D PaulingDinesh Khanna
Jul 17, 2019·The Journal of Rheumatology·Michael Hughes
Nov 12, 2019·British Journal of Hospital Medicine·Vikrant Devgire, Michael Hughes
Aug 30, 2018·Rheumatology International·Olivia QiuEvelyn R Hermes-DeSantis
Apr 26, 2019·Frontiers in Pharmacology·Barbara RuaroAlberto Sulli
Nov 18, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Ashraful Haque, Michael Hughes
Dec 11, 2021·Frontiers in Neurology·Sarah Renno-BuschWalter Maetzler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cephalalgia : an International Journal of Headache
R M JensenR H Jensen
Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology
Gonçalo FernandezMargarida Roldão
© 2022 Meta ULC. All rights reserved