Prediction and Potential Preventions for the Development of Posttraumatic Osteoarthritis after the Terrible Triad Injury: A Multicenter Risk Factors Study.

BioMed Research International
Jingjing LiWeijun Guo

Abstract

A multicenter study to evaluate risk factors for the development of moderate or severe posttraumatic osteoarthritis (PTOA) and to find potential preventions. We conducted a retrospective multicenter study including the terrible triad injury (TTI) patients with surgical treatment from January 2007 to November 2014. Demographics, injury information, and treatment history were obtained retrospectively. According to the Broberg and Morrey criterion, 198 included patients were sorted into two groups: the mild or no PTOA and moderate or severe PTOA. Uni- and multivariate logistic regression analyses were used to identify risk factors for moderate or severe PTOA. Moderate or severe PTOA was present in 64 patients (32.3%). Significant risk factors were Mason III radial head fracture (OR 4.049, 95% CI 1.877-8.736, p < 0.001), medial collateral ligament injury (OR 5.120, 95% CI 1.261-20.790, p = 0.022), and heavy use of elbow (OR 2.333, 95% CI 1.060-5.136, p = 0.035). Besides, patients suffered subluxation (p = 0.007) and those with more risk factors had a higher risk to develop moderate or severe PTOA. Moderate or severe PTOA was common after the TTI. Patients need to be counseled about avoiding heavy use of the elbow, especially for th...Continue Reading

References

Jan 1, 1980·Journal of Biomechanics·A A AmisV Wright
Jan 7, 2000·The American Journal of Medicine·A C GelberM J Klag
Sep 5, 2002·The Journal of Bone and Joint Surgery. American Volume·Jesse B Jupiter, David Ring
Jun 3, 2004·The Journal of Bone and Joint Surgery. American Volume·David M W PughMichael D McKee
Feb 5, 2008·The Journal of Bone and Joint Surgery. American Volume·Benjamin J ShoreGraham J W King
May 2, 2008·Journal of Orthopaedic Trauma·Anneluuk L C LindenhoviusPeter Kloen
Jun 3, 2009·The Journal of Bone and Joint Surgery. American Volume·Andrea Celli, Bernard F Morrey
May 8, 2010·International Orthopaedics·Juan Rodriguez-MartinRicardo Larrainzar-Garijo
Oct 19, 2010·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Woong-Kyo JeongWon-Seok Lee
Oct 22, 2010·The Journal of Hand Surgery·Thierry G GuittonDavid Ring
Jan 18, 2012·International Orthopaedics·Anne LübbekeMathieu Assal
Apr 12, 2012·Acta orthopaedica et traumatologica turcica·Tulgar TorosSait Ada
Nov 3, 2012·The Journal of the American Academy of Orthopaedic Surgeons·Benjamin W SearsBernard F Morrey
Feb 9, 2013·The Journal of Hand Surgery·Loukia K PapatheodorouDean G Sotereanos
Jun 20, 2013·Arthritis·Debdut BiswasMark S Cohen
Oct 19, 2013·Clinical Orthopaedics and Related Research·Tyler Steven WattersDavid S Ruch
Jan 28, 2014·Orthopaedics & Traumatology, Surgery & Research : OTSR·M Chammas
Sep 17, 2014·Annals of Biomedical Engineering·Thomas P AndriacchiConstance R Chu
Nov 28, 2015·Best Practice & Research. Clinical Rheumatology·E Clare Harris, David Coggon
Jan 10, 2016·Injury·Giuseppe GiannicolaStefano Gumina
Aug 2, 2016·Journal of Orthopaedic Trauma·Dafang ZhangNeal Chen
Oct 14, 2016·Nature Reviews. Disease Primers·Johanne Martel-PelletierJean-Pierre Pelletier
Jan 7, 2017·The Journal of Bone and Joint Surgery. American Volume·Brandon J Erickson, Anthony A Romeo
Feb 6, 2017·The Journal of Hand Surgery·Lauren E Karbach, John Elfar
May 4, 2017·Acta Orthopaedica·Jens NestorsonLars Adolfsson
Jun 22, 2017·Archives of Orthopaedic and Trauma Surgery·Junren ZhangErnest Beng Kee Kwek
Feb 17, 2018·Circulation·Zengwu WangUNKNOWN China Hypertension Survey Investigators
May 5, 2018·Annals of the Rheumatic Diseases·Anna Karin HedströmLars Alfredsson
Aug 14, 2018·Journal of medical and biological engineering·Sergey StrafunJan Awrejcewicz
Oct 18, 2018·Current Reviews in Musculoskeletal Medicine·Samuel O EwalefoMaCalus V Hogan
Jan 12, 2019·Journal of Orthopaedic Trauma·Sung-Weon JungGwang-Eun Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Arthritis Research & Therapy
Li-Juan WangGuo-Xin Ni
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Melanie E MendezGabriela G Loots
The Journal of the American Academy of Orthopaedic Surgeons
Mara L SchenkerSamir Mehta
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Carina L BlakerChristopher B Little
© 2021 Meta ULC. All rights reserved