Prediction of 10-year coronary heart disease risk in Caribbean type 2 diabetic patients using the UKPDS risk engine

International Journal of Cardiology
C E EzenwakaJ Eckel

Abstract

Primary prevention of Coronary Heart Disease (CHD) in diabetic patients should be based on absolute CHD risk calculation. This study was aimed to determine the levels of 10-year CHD risk in Caribbean type 2 diabetic patients using the diabetes specific United Kingdom Prospective Diabetes Study (UKPDS) risk engine calculator. Three hundred and twenty-five (106 males, 219 females) type 2 diabetic patients resident in two Caribbean Islands of Tobago and Trinidad met the UKPDS risk engine inclusion criteria. Records of their sex, age, ethnicity, smoking habit, diabetes duration, systolic blood pressure, total cholesterol, HDL-cholesterol and glycated haemoglobin were entered into the UKPDS risk engine calculator programme and the absolute 10-year CHD and stroke risk levels were computed. The 10-year CHD and stroke risks were statistically stratified into <15%, 15-30% and >30% CHD risk levels and differences between patients of African and Asian-Indian origin were compared. In comparison with patients in Tobago, type 2 diabetic patients in Trinidad, irrespective of gender, had higher proportion of 10-year CHD risk (10.4 vs. 23.6%, P<0.001) whereas the overall 10-year stroke risk prediction was higher in patients resident in Tobago (...Continue Reading

References

Jan 1, 1991·American Heart Journal·K M AndersonW B Kannel
Nov 29, 2001·Clinical Science·R J StevensUNKNOWN United Kingdom Prospective Diabetes Study (UKPDS) Group
Aug 7, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Chidum E Ezenwaka, Risha Kalloo
Aug 18, 2004·Annals of Epidemiology·Latha PalaniappanStephen P Fortmann
Oct 19, 2005·Annals of Internal Medicine·UNKNOWN Combination Pharmacotherapy and Public Health Research Working Group
Feb 28, 2006·Atherosclerosis. Supplements·Nita G Forouhi, Naveed Sattar
Aug 23, 2006·Neurology·S RulandUNKNOWN AAASPS Investigators

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Citations

Nov 23, 2011·Archives of Physiology and Biochemistry·C E EzenwakaC Phillip
Nov 4, 2011·Archives of Physiology and Biochemistry·C Ezenwaka, J Eckel

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