Prediction of acidemia at birth by Doppler assessment of fetal cerebral transverse sinus in pregnancies with placental insufficiency

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
M M BarbosaA F Moron

Abstract

To evaluate the prediction of acidemia at birth using cerebral transverse sinus (CTS) Doppler velocimetry and to determine the best parameter and cut-off values for its prediction in pregnancies complicated with placental insufficiency. This was a prospective cross-sectional study involving 69 pregnant women (26-40 weeks' gestation) with placental insufficiency managed in two Brazilian hospitals. Doppler assessment of the CTS was carried out in the last 24 h before delivery, and the peak ventricular systolic (S-wave) and diastolic (D-wave) velocities as well as the atrial systolic velocity (A-wave) were recorded and the pulsatility index for veins (PIV) was calculated. At birth, arterial and venous umbilical cord blood samples were collected to determine acid-base and pH status. A receiver-operating characteristics (ROC) curve was constructed for each Doppler parameter with birth acidemia as the dependent variable. Sensitivity, specificity, positive and negative predictive values, accuracy and false-positive and false-negative rates were calculated for the parameters considered to be good predictors of acidemia. The S, D and A peak velocities and the S/A ratio were not good predictors of acidemia at birth. The PIV and the (S - ...Continue Reading

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Citations

Apr 25, 2012·Archives of Gynecology and Obstetrics·Luciano Marcondes Machado NardozzaA F Moron

Related Concepts

Metabolic Acidosis
Blood Flow Velocity
Structure of Cerebral Artery
Cerebrovascular Circulation
Prevalence Studies
Embryopathies
Placental Insufficiency
Pulsatile Flow
Receiver Operating Characteristic
Fetal Ultrasonography

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