Prediction of biomechanical responses of human lumbar discs - a stochastic finite element model analysis.

Computer Methods in Biomechanics and Biomedical Engineering
Wei WangGuoan Li

Abstract

Accurate biomechanical investigation of human intervertebral discs (IVDs) is difficult because of their complicated structural and material features. To investigate probabilistic distributions of the biomechanical responses of the IVD by considering varying nonlinear structural and material properties using a stochastic finite element (FE) model. A FE model of a L3-4 disc was reconstructed, including the nucleus pulposus (NP), annular matrix and fibers. A Monte Carlo method was used to randomly generate 500 sets of the nonlinear material properties and fiber orientations of the disc that were implemented into the FE model. The FE model was analyzed under seven loading conditions: a 500 N compressive force, a 7.5Nm moment simulating flexion, extension, left-right lateral bending, and left-right axial rotation, respectively. The distributions of the ranges of motion (ROMs), intradiscal pressures (IDP), fiber stresses and matrix strains of the disc were analyzed. Under the compressive load, the displacement varied between 0.29 mm and 0.76 mm. Under the 7.5Nm moment, the ROMs varied between 3.0° and 6.0° in primary rotations. The IDPs varied within 0.3 MPa under all the loading conditions. The maximal fiber stress (3.22 ± 0.64 MPa)...Continue Reading

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