Prediction of Clinical Outcome at Discharge After Rupture of Anterior Communicating Artery Aneurysm Using the Random Forest Technique

Frontiers in Neurology
Nengzhi XiaJinjin Liu

Abstract

Background: Aneurysmal subarachnoid hemorrhage (SAH) is a devastating disease. Anterior communicating artery (ACoA) aneurysm is the most frequent location of intracranial aneurysms. The purpose of this study is to predict the clinical outcome at discharge after rupture of ACoA aneurysms using the random forest machine learning technique. Methods: A total of 607 patients with ruptured ACoA aneurysms were included in this study between December 2007 and January 2016. In addition to basic clinical variables, 12 aneurysm morphologic parameters were evaluated. A multivariate logistic regression analysis was performed to determine the independent predictors of poor outcome. Of the 607 patients, 485 patients were randomly selected for training and the remaining for internal testing. The random forest model was developed using the training data set. An additional 202 patients from February 2016 to December 2017 were collected for externally validating the model. The prediction performance of the random forest model was compared with two radiologists. Results: Patients' age (odds ratio [OR] = 1.04), ventilated breathing status (OR = 4.23), World Federation of Neurosurgical Societies (WFNS) grade (OR = 2.13), and Fisher grade (OR = 1.50)...Continue Reading

References

Mar 1, 1975·Lancet·B Jennett, M Bond
Sep 1, 2006·The New England Journal of Medicine·Jonathan L BrismanDavid W Newell
Jan 30, 2007·Lancet·Jan van GijnGabriel J E Rinkel
Jul 12, 2008·Stroke; a Journal of Cerebral Circulation·Nestor GonzalezFernando Vinuela
Apr 17, 2009·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Paula de ToledoAlfonso Lagares
Feb 9, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S-Y PengK-H Tseng
May 2, 2012·Genomics·Xi Chen, Hemant Ishwaran
Dec 15, 2012·Stroke; a Journal of Cerebral Circulation·Hui LiYing Peng
Dec 18, 2012·Journal of Neurosurgery·Hidetoshi MatsukawaSosuke Sumiyoshi
May 22, 2016·Computer Methods and Programs in Biomedicine·Zerina Masetic, Abdulhamit Subasi
Oct 5, 2017·Stroke; a Journal of Cerebral Circulation·James P GaleaUNKNOWN UK and Ireland Subarachnoid Hemorrhage Database Collaborators
Oct 8, 2017·World Neurosurgery·Joeky T SendersOmar Arnaout
Oct 24, 2017·Frontiers in Aging Neuroscience·Alessia SaricaAldo Quattrone

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