Prediction of coronary artery disease in patients with lower extremity peripheral artery disease

International Heart Journal
Sung Woo ChoChoong Won Goh

Abstract

Coronary artery disease (CAD) is a major determinant of long-term prognosis in patients with peripheral artery disease (PAD). We investigated the predictors of CAD in patients with lower extremity PAD.A total of 107 patients with PAD who underwent peripheral and simultaneous coronary angiography were reviewed. PAD was defined as (≥ 50%) stenosis associated with claudication or critical limb ischemia. PAD was divided into proximal and distal lesions. CAD was defined as angiographically significant (≥ 50%) stenosis of coronary arteries.The prevalence of CAD in patients with PAD was 62% (67/107), and of this 62%, only 13% (9/67) had angina and 72% (48/67) had multi-vessel disease. Diabetes significantly increased the risk of CAD in patients with PAD and the odds ratio of having multi-vessel CAD was 2.5 (1.1-5.9, P = 0.037) in multivariate regression analysis. The patients with multi-vessel CAD had more cardiovascular risk factors than those with normal, minimal and single CAD (P = 0.032). Interestingly, the prevalence of proximal PAD was higher in the normal or single CAD group than the multi-vessel CAD group, whereas both proximal and distal involvement of PAD was higher in the multi-vessel CAD group.Diabetes, multi-cardiovascula...Continue Reading

References

May 12, 2005·Journal of Vascular Surgery·Thomas F RehringH Whitton Hollis
Nov 5, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·N DiehmI Baumgartner
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Apr 19, 2008·Journal of the American College of Cardiology·Gijs M J M WeltenDon Poldermans
Mar 9, 2010·Heart & Lung : the Journal of Critical Care·Nilüfer Ekşi DuranMehmet Ozkan
May 29, 2012·The American Journal of Cardiology·David J HurEllen C Keeley
Oct 25, 2012·JAMA : the Journal of the American Medical Association·Michel M JoostenKenneth J Mukamal
Oct 23, 2013·Journal of the American Heart Association·Qian ChenIftikhar J Kullo
Apr 3, 2014·Current Atherosclerosis Reports·Rasmus Sejersten RipaBirger Hesse

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Citations

Jul 5, 2016·Annals of Vascular Diseases
Dec 30, 2015·The International Journal of Lower Extremity Wounds·Janis VellaGodfrey LaFerla
Jan 1, 2016·Vascular·Marko NovakovicHelena Lenasi
Dec 4, 2019·VASA. Zeitschrift für Gefässkrankheiten·Ulrich FrankPiotr Terlecki

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