Prediction of esophageal varices in cirrhotic patients with apparent diffusion coefficient of the spleen

Abdominal Imaging
Ahmed Abdel Khalek Abdel RazekEnas Mohamed Motawea

Abstract

To predict esophageal varices in cirrhotic patients with apparent diffusion coefficient (ADC) of the spleen and to correlate the ADC with clinical and laboratory biomarkers of esophageal varices. This study was conducted upon 40 patients (28 male, 12 female; age ranged 19-45 years; mean age = 33 years) with biopsy-proven cirrhotic liver. Twenty age- and sex-matched healthy volunteers were included as a control group. Patients with varices (n = 15) and without varices (n = 25) and volunteers underwent echo-planar diffusion-weighted MR imaging of the abdomen with b factors of 0, 400, and 800 s/mm(2). The ADC maps of the abdomen were reconstructed. The ADC values of the spleen were calculated and correlated with the Child score, platelet count, and prothrombin time. The mean ADC value of the spleen in cirrhotic patients (1.34 ± 0.05 × 10(-3) mm(2)/s) was significantly different (P = 0.001) from that of volunteers (0.87 ± 0.04 × 10(-3) mm(2)/s). The ADC of the spleen in cirrhotic patients with varices (1.49 ± 0.05 × 10(-3) mm(2)/s) was significantly different (P = 0.001) from that of patients without varices (1.11 ± 0.06 × 10(-3) mm(2)/s). The cut-off ADC value of the spleen used for prediction of cirrhosis and varices was 1.15 and...Continue Reading

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Citations

Oct 29, 2018·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·N E El-AshmawyO A El-Feky
Sep 26, 2019·Abdominal Radiology·Yoshifumi NodaMasayuki Matsuo
Jan 16, 2020·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel RazekWalaa Shabana
Mar 21, 2020·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel RazekRihame Abd El-Wahab
Aug 26, 2020·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel RazekEman Alnaghy
Mar 29, 2019·World Journal of Gastroenterology : WJG·Tarek BesheerMahmoud El-Bendary
Jul 31, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ahmed Abdel Khalek Abdel RazekTarik Barakat
Aug 11, 2020·World Journal of Gastroenterology : WJG·Qun-Yan YaoGuang-Qi Song
Dec 4, 2019·British Journal of Biomedical Science·Mahmoud El-BendaryMustafa Neamatallah
Nov 3, 2020·World Journal of Gastroenterology : WJG·Neta GotliebOren Shibolet
Apr 3, 2021·BMC Gastroenterology·Xiaojuan ZouZhenyu Jiang
Apr 30, 2021·Japanese Journal of Radiology·Ahmed Abdel Khalek Abdel RazekTarek Elsayed Barakat

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