Prediction of gene function in methylthioadenosine recycling from regulatory signals.

Journal of Bacteriology
Brooke A MurphyTina M Henkin

Abstract

The S-box transcription termination control system, first identified in Bacillus subtilis, is used for regulation of gene expression in response to methionine availability. The presence of the S-box motif provided the first indication that the ykrTS and ykrWXYZ genes could play a role in recycling of 5'-methylthioadenosine, a by-product of polyamine biosynthesis that can be converted to methionine. In this study we demonstrate a role for the ykrTS and ykrWXYZ gene products in this pathway.

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Citations

Mar 3, 2004·Research in Microbiology·Marie-Françoise HulloIsabelle Martin-Verstraete
Dec 13, 2006·Nature Biotechnology·Kenneth F Blount, Ronald R Breaker
Jun 25, 2004·Nucleic Acids Research·Dmitry A RodionovMikhail S Gelfand
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Mar 5, 2009·Microbiology and Molecular Biology Reviews : MMBR·Ana Gutiérrez-PreciadoEnrique Merino
Apr 30, 2008·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Joy Xin Wang, Ronald R Breaker
Oct 6, 2005·BMC Microbiology·Alexander V SeliverstovVassily A Lyubetsky
Apr 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·Vitaly EpshteinEvgeny Nudler
Mar 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Brooke A Murphy McDanielTina M Henkin
Feb 26, 2008·Plant Physiology and Biochemistry : PPB·Inger Andersson, Anders Backlund
Apr 5, 2003·Current Biology : CB·Eric C Lai
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May 25, 2007·The Journal of Biological Chemistry·Shao-Yang KuP Lynne Howell

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