Prediction of live birth and cumulative live birth rates in freeze-all-IVF treatment of a general population

Journal of Assisted Reproduction and Genetics
Kemal OzgurKevin Coetzee

Abstract

To investigate the cumulative live birth (cLB) rate of one complete freeze-all-IVF cycle in a general infertile population and to investigate patient and treatment variables that predict blastocyst development and live birth (LB). In a retrospective observational study, the data of all IVF cycles performed between 1 February 2015 and 31 January 2016 at a single IVF centre was investigated. In the study, patient-couples were followed up for 18 months following oocyte retrieval. After exclusions, the patient and treatment variables of 1582 patient-couples who underwent treatment were included in the analyses. The median time interval between the oocyte retrieval attempt and the frozen embryo transfer (FET) in which LB was achieved was 38.0 (35.0-67.0) days. The variables of freeze-all-IVF cycles with single blastocyst FET selected by multiple logistic regression to predict LB significantly were female age, infertility duration, FET number (i.e. 1st, 2nd, or ≥ 3rd FET), and blastocyst quality. In a regression adjusting for female age, the number of blastocysts transferred, and oocyte number group (1-3, 4-9, 10-15, and > 15), none of the oocyte number groups were selected to predict LB of 1st FET, significantly. While the per trans...Continue Reading

References

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Dec 25, 2015·Journal of Assisted Reproduction and Genetics·Kemal OzgurKevin Coetzee
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Jun 12, 2016·Reproductive Biology·Kemal OzgurKevin Coetzee
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Feb 13, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Kemal OzgurKevin Coetzee

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Citations

Dec 24, 2019·Human Reproduction Update·Yossi MizrachiAriel Weissman
Jan 5, 2020·Journal of Assisted Reproduction and Genetics·Zhiren LiuYun Liu
Apr 25, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Kemal OzgurKevin Coetzee
Apr 24, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sidse HøyerJørn Aagaard

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