PMID: 8986979Dec 1, 1996Paper

Prediction of morbidity during infancy after repair of congenital diaphragmatic hernia

Journal of Pediatric Surgery
S NaikM Davenport

Abstract

Recent studies have suggested there may be a high incidence of pulmonary and extrapulmonary sequelae among infants who have undergone repair of congenital diaphragmatic hernia (CDH). The aim of this study was to identify factors that predict high-risk cases to facilitate counseling of parents. Morbidity, defined as conditions requiring treatment and/or hospitalization during follow-up, was documented. Only five of 15 cases that had been diagnosed antenatally (at 16 to 26 weeks' gestation) and underwent surgical repair after preoperative stabilization were without morbidity at the time of follow-up. Respiratory problems were identified in seven (chylothorax in 3, recurrent infections in 4) and failure to thrive in four; three infants required further gastrointestinal surgery. A comparison of infants with and without morbidity showed that the only significant difference between the groups was in the duration of respiratory support. A requirement for respiratory support for more than 10 days had 90% sensitivity, 100% specificity, and a positive predictive value for morbidity at follow-up of 100%.

Citations

Aug 4, 2010·Pediatric Surgery International·Alejandro ZavalaJavier Kattan
Jun 5, 2003·Journal of Pediatric Surgery·M N HanekampR R Postema
Nov 5, 1999·British Journal of Obstetrics and Gynaecology·C L HuddyP Chamberlain
Sep 13, 2008·World Journal of Surgery·Caroline ChamondSylvie Beaudoin
Jun 16, 2009·Journal of Pediatric Surgery·Raquel GonzalezGeorge B Mychaliska
Apr 28, 2007·Seminars in Pediatric Surgery·Pietro Bagolan, Francesco Morini
Oct 11, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J C JaniUNKNOWN Antenatal-CDH-Registry group
Jun 14, 2008·Prenatal Diagnosis·Priscilla Chiu, Holly L Hedrick
Jun 13, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R Cruz-MartinezE Gratacos
Mar 3, 1999·Journal of Pediatric Surgery·L SchoemanD P Drake
Apr 16, 2013·Journal of Pediatric Surgery·Shauna M LevyUNKNOWN Congenital Diaphragmatic Hernia Study Group
Jul 30, 2002·Neonatal Network : NN·J Braby
Aug 18, 2006·Neonatal Network : NN·Barbara Puckett
Apr 16, 1998·Journal of Pediatric Surgery·V KavvadiaK H Nicolaides
Apr 1, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R L KellerC T Albanese
Apr 2, 2014·Pediatrics·James D Tutor
Dec 11, 2021·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Rim KiblawiJens Dingemann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.