Prediction of neurological deficits and recovery after surgery in the supplementary motor area: a prospective study in 26 patients

Journal of Neurosurgery
Keren RosenbergZvi Ram

Abstract

Resection of lesions involving the supplementary motor area (SMA) may result in immediate postoperative motor and speech deficits that are reversible in most cases. In the present study the authors aimed to determine the critical involvement of SMA in the lesioned and healthy hemispheres in this functional recovery. They hypothesized that compensatory mechanisms take place following surgery in the SMA, and that these mechanisms can involve either the lesioned or the non-lesioned hemisphere. In addition, they hypothesized that a correlation will be present between the functional MR imaging (fMR) imaging-related activation in the SMA and the occurrence of a functional deficit during intraoperative cortical stimulation. Twenty-six patients scheduled for resection of space-occupying lesions involving, or in the vicinity of, the SMA were recruited. Patients underwent an fMR imaging examination that included finger-tapping and verb-generation tests to assess for motor and language functions. Intraoperatively direct cortical stimulation (DCS) of the SMA region was performed while patients were monitored for language and motor functions using tests similar to those used for the fMR imaging. Task dysfunction during DCS assessed the crit...Continue Reading

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Citations

May 7, 2013·Journal of Neurosurgery·Nicholas M Barbaro
Jan 2, 2014·Journal of Neuroradiology. Journal De Neuroradiologie·Mehrnaz JenabiAndrei I Holodny
Feb 11, 2015·Epilepsy & Behavior Case Reports·Van Tri TruongDang Khoa Nguyen
Dec 7, 2013·Neurologia Medico-chirurgica·Satoru HiroshimaKyousuke Kamada
Dec 17, 2014·Frontiers in Human Neuroscience·A R E PotgieserR J M Groen
Jan 28, 2017·Epilepsy Research·Melissa van OffenFrans S Leijten
Nov 28, 2013·Journal of Korean Neurosurgical Society·Kyung Hyun KimSang Hyung Lee
Sep 16, 2020·Current Neurology and Neuroscience Reports·Mar Jiménez de la PeñaManuel Recio Rodríguez
Feb 6, 2017·Journal of Neurosurgery·Mario A Alonso-VanegasCarlos Trenado
Jun 8, 2018·Frontiers in Psychology·Alba CañasMireia Hernández
Mar 8, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jonathan Roth, Shlomi Constantini
Nov 11, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nardin SamuelMichael D Taylor
Feb 6, 2016·Topics in Magnetic Resonance Imaging : TMRI·Nicole Petrovich BrennanAndrei Holodny

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Methods Mentioned

BETA
SMA
imaging techniques
sedation
intact

Software Mentioned

BrainVoyager
Presentation
STATISTICA

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