PMID: 9164685May 1, 1997Paper

Prediction of obliteration of arteriovenous malformations after radiosurgery: the obliteration prediction index

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
M SchwartzE Franssen

Abstract

To describe the response to single dose photon stereotactic radiosurgery of arteriovenous malformations (AVMs) so that the probability of success or failure of treatment may be predicted for the individual patient. The obliteration prediction index (OPI) was calculated for AVMs by dividing the marginal dose of radiation in Gray (Gy) by the lesion diameter in centimetres in cohorts of 42 patients treated with the modified linear accelerator at Toronto-Sunnybrook Regional Cancer Centre and 394 patients treated with the gamma unit at the Royal Hallamshire Hospital, Sheffield, United Kingdom. Patients were grouped into ranges by OPI and the proportion of success and failure was calculated for each group. An exponential function [P = 1-A.e(-B.OPI)] was fitted to the data by the least squares method. Despite systematic differences in radiation treatment, that is, marginal doses of 15 and 20 Gy in Toronto and most Sheffield patients with a marginal dose of 25 Gy, the resultant data points exhibited similar behaviour. The function [P = 1-A.e(-B.OPI)] partly describes the biological effect of radiation and is independent of the radiation device used. Radiosurgery centres can use this model to facilitate predictions of successful treatme...Continue Reading

References

Jul 1, 1992·Journal of Neurosurgery·L SteinerM Steiner
Jan 1, 1992·British Journal of Neurosurgery·J C SutcliffeA A Kemeny
Oct 1, 1991·Journal of Neurosurgery·L D LunsfordR J Coffey
May 1, 1991·Medical Physics·P F O'BrienP Davey
Aug 1, 1991·Journal of Neurosurgery·L B Marks, D P Spencer
Sep 1, 1990·International Journal of Radiation Oncology, Biology, Physics·L SouhamiG B Pike
May 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·A A KemenyD M Forster
Jan 1, 1988·International Journal of Radiation Oncology, Biology, Physics·E B PodgorsakJ Hazel
Oct 15, 1994·International Journal of Radiation Oncology, Biology, Physics·R EngenhartM Wannenmacher

❮ Previous
Next ❯

Citations

Jan 24, 2008·Acta neurochirurgica·Y M Andrade-SouzaM L Schwartz
Nov 4, 2000·Neurosurgery·B E Pollock
Apr 19, 2008·Stereotactic and Functional Neurosurgery·Robert M StarkeE Sander Connolly
Sep 15, 2006·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·M SödermanT Andersson
Aug 28, 2012·Neurosurgery·Patamintita TaeshineetanakulMichael L Schwartz
Aug 25, 2018·AJNR. American Journal of Neuroradiology·H HasegawaN Saito
May 1, 1997·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·N J Laperriere, M Bernstein
Nov 24, 2006·Journal of Neurosurgery·Yuri M Andrade-SouzaMichael L Schwartz
Mar 1, 2007·Neurosurgery·Yuri M Andrade-SouzaMichael L Schwartz
Aug 13, 2002·Physics in Medicine and Biology·Panayiotis MavroidisAnders Brahme
Dec 24, 2011·AJNR. American Journal of Neuroradiology·F BingA Weill
Feb 20, 2013·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Magali Lecavalier-BarsoumJean-Paul Bahary
May 2, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P DaveyB Gillies
May 8, 2018·Neurosurgical Review·Ali Tayebi Meybodi, Michael T Lawton
Jun 2, 2006·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Javad Mirza-AghazadehMichael L Schwartz
Jan 17, 2002·Journal of Neurosurgery·Bruce E Pollock, John C Flickinger
Sep 2, 2014·Neurosurgical Focus·Kenan AlKhaliliPascal Jabbour
Jun 5, 2018·World Neurosurgery·Stéphanie LenckIvan Radovanovic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.