PMID: 6538165Feb 1, 1984Paper

Prediction of ocular irritancy potential from dermal irritation test results

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
S J Williams

Abstract

In a survey of the test files of Haskell Laboratory, it was found that of the materials that had been tested on rabbit skin for primary irritation or corrosivity, 60 were severe irritants or corrosive on the skin and had also been tested for ocular irritancy. Of these 60 materials only 39 were severe eye irritants, while 15 were mild irritants or non-irritants and the remainder were considered to be moderate irritants. Thus, to suggest that materials are eye irritants solely on the basis of their skin-irritation properties may be misleading, even when severe dermal irritants are considered.

References

Jun 1, 1971·Toxicology and Applied Pharmacology·C S Weil, R A Scala
Mar 1, 1962·American Industrial Hygiene Association Journal·H F SMYTHJ A STRIEGEL

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Citations

Aug 11, 1992·Journal of Applied Toxicology : JAT·G L Kennedy, A K Banerjee
Feb 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S J Williams
Feb 1, 1993·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·P M HurleyD K Lowther
Aug 1, 1994·Toxicology in Vitro : an International Journal Published in Association with BIBRA·R W LewisP A Botham
Feb 1, 1994·Toxicology in Vitro : an International Journal Published in Association with BIBRA·R W LewisP A Botham
Jun 1, 1995·Toxicology in Vitro : an International Journal Published in Association with BIBRA·H KojimaI Yoshimura
Jun 27, 2001·Survey of Ophthalmology·K R Wilhelmus
Jan 1, 1991·Critical Reviews in Toxicology·G D Nielsen
Mar 29, 2000·Archives of Environmental Health·R C Anderson, J H Anderson
Sep 29, 1999·Archives of Environmental Health·R C Anderson, J H Anderson
Aug 12, 1999·Archives of Environmental Health·R C Anderson, J H Anderson
May 15, 2003·Journal of Toxicology and Environmental Health. Part a·Rosalind C Anderson, Julius H Anderson
Nov 1, 1993·Toxicology and Industrial Health·I H Chu, P Toft

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