Prediction of postoperative complications and survival after laparoscopic gastrectomy using preoperative Geriatric Nutritional Risk Index in elderly gastric cancer patients.

Surgical Endoscopy
Noriyuki HiraharaTakahito Taniura

Abstract

Preoperative nutritional assessment of cancer patients is important to reduce postoperative complications. Several studies have reported the Geriatric Nutritional Risk Index (GNRI) to be useful in assessing underlying diseases and long-term outcomes of hospitalized patients. The present study aimed to evaluate the impact of preoperative GNRI on short- and long-term outcomes in elderly gastric cancer patients who underwent laparoscopic gastrectomy. We retrospectively reviewed consecutive patients aged ≥ 65 years who underwent laparoscopy-assisted gastrectomy and had R0 resection for histologically confirmed gastric adenocarcinoma. The cutoff value for preoperative GNRI was determined to be 85.7 based on the incidence of postoperative complications. Patients were categorized into two groups: low GNRI group and normal GNRI group. Univariate analyses of the 303 patients revealed that the incidence of postoperative complications was significantly associated with the American Society of Anesthesiologists Physical Status classification (ASA-PS), C-reactive protein (CRP), GNRI (p < 0.001), and operative procedure. Multivariate analyses revealed that preoperative GNRI (odds ratio [OR] 2.716; 95% confidence interval [CI] 1.166-6.328; p =...Continue Reading

References

Oct 8, 2005·The American Journal of Clinical Nutrition·Olivier BouillanneChristian Aussel
Feb 29, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Malgorzata Krzystek-KorpackaAndrzej Gamian
Jul 30, 2009·Annals of Surgery·Pierre A ClavienMasatoshi Makuuchi
Nov 26, 2010·Upsala Journal of Medical Sciences·Sándor MártonSubhamay Ghosh
Dec 31, 2010·International Journal of Colorectal Disease·Cheng-Chou LaiChih-Chien Chin
Nov 21, 2012·Nutrition and Cancer·Aline Kirjner PoziomyckLuis Fernando Moreira
Jan 15, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Wafaa Mostafa Abd-El-GawadGhada Essam Amin
Sep 2, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Judy Wc HoSuk-on Lee
Mar 21, 2015·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·Ippei YamanaYuichi Yamashita
Jun 28, 2016·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
Feb 10, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Maria Antonelli, Irving Kushner
Feb 17, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·S SzeA L Clark
Jul 5, 2017·Autoimmunity·Liying ChenKonstantin Yakimchuk
Dec 10, 2017·Asia Pacific Journal of Clinical Nutrition·Hui WangBi-Rong Dong
Feb 2, 2018·Annals of Surgical Oncology·Keiichi FujiyaMasanori Terashima
Jun 1, 2018·Anticancer Research·Sho SawazakiMunetaka Masuda
Jun 26, 2018·The Journal of Surgical Research·Mubina A IsaniEugene S Kim
Aug 30, 2018·Molecular and Clinical Oncology·Naotake FunamizuKazunao Kurihara
Sep 15, 2018·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E C GertsenUNKNOWN Dutch Upper Gastrointestinal Cancer Audit (DUCA) group
Oct 13, 2018·Esophagus : Official Journal of the Japan Esophageal Society·Naoshi KuboMasaichi Ohira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.