Prediction of suboptimal cytoreductive surgery in patients with advanced ovarian cancer based on preoperative and intraoperative determination of the peritoneal carcinomatosis index

World Journal of Surgical Oncology
Antoni LluecaMUAPOS working group (Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery)

Abstract

The peritoneal carcinomatosis index (PCI) can be used to quantify the tumor burden in patients with advanced ovarian cancer. The aim of the present study was to establish a predictive model for suboptimal cytoreductive surgery (SCS) (residual tumor of > 1 cm) using preoperative and intraoperative determination of the PCI. In total, 110 consecutive patients treated for advanced ovarian cancer during a 4-year period in our institution were assessed. Eighty of these patients were eligible for primary debulking surgery and thus included in the present study. All data were prospectively collected and retrospectively evaluated. We determined the PCI both preoperatively and intraoperatively and assessed postoperative complications. A PCI of > 20 was the best cut-off with which to predict a risk of SCS among all three diagnostic techniques assessed in this study (computed tomography, laparoscopy, and laparotomy). Intraoperative PCI determination was associated with the lowest risk of false negatives for SCS when detecting a PCI of < 20. The combination of preoperative computed tomography and laparoscopy, when both techniques predicted SCS, was associated with the lowest risk of false positives for SCS when detecting a PCI of > 20. The ...Continue Reading

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Citations

Apr 18, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Antoni Llueca, Javier Escrig
May 22, 2019·The British Journal of Radiology·Shimaa Abdalla AhmedDalia M Badary
Jun 4, 2020·Expert Opinion on Pharmacotherapy·Eelco de Bree, Dimosthenis Michelakis
Mar 9, 2020·Journal of Ovarian Research·Hanna SartorKarin Jirström
May 30, 2020·Annals of Surgical Oncology·Karin Stålberg, Björg Jónsdóttir
May 31, 2020·Annals of Surgical Oncology·Björg JónsdóttirKarin Stålberg
Nov 27, 2020·World Journal of Surgical Oncology·Antoni LluecaUNKNOWN on behalf MUAPOS Working Group
Jan 15, 2021·Cancer Management and Research·Antoni LluecaUNKNOWN MUAPOS working group (Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery
Nov 28, 2020·International Journal of General Medicine·Yudi Mulyana HidayatSiti Salima
Apr 5, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Mette Schou MikkelsenLene Hjerrild Iversen
Apr 6, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M P EngbersenW J Van Driel
Apr 16, 2021·Scientific Reports·Antoni LluecaUNKNOWN MUAPOS working group (Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery)
Aug 21, 2021·The British Journal of Radiology·Maurits Peter EngbersenMax Lahaye
Nov 13, 2021·Insights Into Imaging·Panagiota Berta PanagiotopoulouPanos Prassopoulos

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Methods Mentioned

BETA
pancreatectomy
imaging techniques

Software Mentioned

CUSUM

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