Prediction of the level of consciousness using pupillometer measurements in patients with impaired consciousness brought to the emergency and critical care center

Acute Medicine & Surgery
Yosuke MinamiJun Oda

Abstract

We investigated whether the level of consciousness can be predicted using pupillometer measurements in patients with severe disturbance of consciousness. Patients with a Glasgow Coma Scale (GCS) of 3-8, except for those after cardiac arrest, were included. Pupillary contraction rate and contraction velocity were each measured using a pupillometer. Thirty-five patients were analyzed. At the time of discharge or changing hospitals, 16 patients had a GCS score of 3-13 and 19 patients had a GCS score of 14-15. In the non-sedative group at about the time of arrival at our hospital, average pupillary contraction rates were 18.36% in the GCS 3-13 group and 19.67% in the GCS 14-15 group (P = 0.739), and average pupillary contraction velocities were 1.02 and 1.48, respectively (P = 0.182). Approximately 48 h after arrival, average pupillary contraction rates were 21.18% and 29.27%, respectively (P = 0.058), and average pupillary contraction velocities were 1.37 and 1.91, respectively (P = 0.172). Among the sedative group, at about the time of arrival, average pupillary contraction rates were 8.75% in the GCS 3-13 group and 19.75% in the GCS 14-15 group (P = 0.032). Average pupillary contraction velocities were 0.34 and 1.48, respectivel...Continue Reading

References

Apr 8, 2010·Annals of Neurology·Andrea O RossettiPeter W Kaplan
Nov 10, 2010·Annals of Neurology·Jennifer E FugateAlejandro A Rabinstein
Feb 11, 2012·Neurology·Andrea O RossettiMauro Oddo
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sedation

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