PMID: 16615567Apr 18, 2006Paper

Predictive biochemical indicators of a postlaryngectomy pharyngocutaneous fistula: a clinical study

Acta otorrinolaringológica española
C Martín VillaresM Tapia

Abstract

The aim of this clinical study was to determinate biochemical predictor indicators of postlaryngectomy pharyngocutaneous fistula. We have studied 100 patients with T2- 4 a laryngeal and piryform sinus carcinoma who underwent a laryngectomy. All patients were ASA 2-3. We studied serum albumin, protein serum level, cholesterol and lymphocites in each patient. These variables underwent statistical analysis (p < 0.05). 19% of the patients developed a postlaryngectomy pharyngocutaneous fistula, with a long-stay of 25 days vs. 10 days of stay in patients without postlaryngectomy pharyngocutaneous fistula. 7 postlaryngectomy pharyngocutaneous fistula needed surgical repair. Low serum albumin (< 3.5 g/dL) and a low level of serum proteins (< 6.5 g/dL) were predictive indicators of postlaryngectomy pharyngocutaneous fistula (p < 0.05). Our results suggest that a low-level of serum proteins and albumin are predictive clinical parameters of postlaryngeal pharyngocutaneous fistula.

Citations

Sep 24, 2011·Acta Oto-laryngologica·María Cruz Iglesias-MorenoJoaquín Poch-Broto
Apr 21, 2021·Brazilian Journal of Otorhinolaryngology·Tercio Guimarães ReisCarlos Neutzling Lehn

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