PMID: 8448568Feb 1, 1993Paper

Predictive estimate of blood dose from external counting data preceding radioiodine therapy for thyroid cancer

Nuclear Medicine and Biology
S R ThomasH R Maxon

Abstract

Bone marrow depression following 131I therapy for metastatic thyroid cancer can occur in up to one-quarter of all patients so treated. An analysis was made of the 131I whole body (WB) retention and its relationship to activity in blood for 46 patients (45 adult, 1 adolescent in 49 total studies) to define the accuracy of utilizing WB external counting data as a predictor of blood dose in comparison to the more classical method which requires data from sequential blood samples. The mean percentage differences between blood dose estimates based on external WB counting and those calculated by the classical method lie within +/- 10%. The WB methodology provides a useful first-order approximation for hematopoietic dose estimates in adult patients undergoing 131I therapy for thyroid cancer.

Citations

Aug 2, 2008·European Journal of Nuclear Medicine and Molecular Imaging·M LusterUNKNOWN European Association of Nuclear Medicine (EANM)
Oct 1, 1993·Journal of Toxicology and Environmental Health·G K LivingstonH R Elson
Mar 28, 2002·Thyroid : Official Journal of the American Thyroid Association·Douglas Van NostrandLeonard Wartofsky
Mar 28, 2002·Cancer Biotherapy & Radiopharmaceuticals·James C Sisson
Feb 19, 2013·Cancer Biotherapy & Radiopharmaceuticals·Sanam AramiS Abolghasem Haeri
Apr 14, 2005·Clinical Nuclear Medicine·Herbert A KleinLois J Worthy
Sep 12, 2015·Thyroid : Official Journal of the American Thyroid Association·Frank AtkinsLeonard Wartofsky
Apr 23, 2014·Nuclear Medicine Communications·Armaghan Fard-EsfahaniMohammad Eftekhari
Jul 12, 2020·Journal of Pediatric Endocrinology & Metabolism : JPEM·Praveen KumarChandrasekhar Bal
Mar 18, 2006·Arquivos brasileiros de endocrinologia e metabologia·Marcelo Tatit SapienzaMarília M S Marone
Jul 13, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Edward B SilbersteinAlan D Waxman
Apr 15, 2017·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Kenneth J NicholsChristopher J Palestro
Apr 11, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Walter JentzenMarcus Ruhlmann

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