Predictive factors for pancreatic fistula following pancreatectomy

Langenbeck's Archives of Surgery
Matthew T McMillan, Charles M Vollmer

Abstract

Postoperative pancreatic fistula is a significant contributor to morbidity following proximal and distal pancreatic resections. In recent decades, the incidence of fistula has ranged from 2 to 33 %; however, the consistent identification of risk factors has been difficult due to significant variability in the definition of pancreatic fistula. The purpose of this study was to use the highest level evidence available in the literature to present risk factors thus far identified as significant predictors of fistula occurrence. Another endpoint will address those risk factors which have been shown to have a clinical impact on the patient. This review will conclude by discussing comprehensive risk models that interpret the aggregate fistula risk for a patient based on the presence of weighted risk factors. The contemporary surgical literature suggests many risk factors for fistula development, which can be categorized as either endogenous, operative, or perioperative. The advent of the International Study Group of Pancreatic Fistula (ISGPF) scheme created universal definitions for fistula that delineate between biochemical and clinically relevant fistulas. This classification system has allowed for the elucidation of risk factors fo...Continue Reading

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Citations

Sep 1, 2014·Langenbeck's Archives of Surgery·Giuseppe MalleoClaudio Bassi
Feb 21, 2016·Gastroenterology Clinics of North America·Jashodeep Datta, Charles M Vollmer
Sep 17, 2015·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Matthew T McMillanCharles M Vollmer
Oct 31, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Matthew T McMillan, Charles M Vollmer
Aug 8, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·So Hyun ParkMoon-Gyu Lee
Jul 16, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Riccardo CasadeiFrancesco Minni
Oct 13, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Matthew T McMillanCharles M Vollmer
Aug 31, 2017·Current Treatment Options in Gastroenterology·Laura Maggino, Charles M Vollmer
Jul 15, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Matthew T McMillanStephen W Behrman
Nov 10, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Kai Wang, Ying Fan
Nov 28, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ozgur AkgulTimothy M Pawlik
Oct 23, 2020·Annals of Surgical Oncology·George Van Buren, Charles M Vollmer
Nov 17, 2019·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Elizaveta VasilyevaPeter Tw Kim

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