Predictive Factors for the Rate of Visual Field Progression in the Advanced Imaging for Glaucoma Study

American Journal of Ophthalmology
Xinbo ZhangAdvanced Imaging for Glaucoma Study Group

Abstract

To investigate predictive factors associated with the rate of visual field (VF) loss in open-angle glaucoma. Prospective multicenter cohort study. Perimetric glaucoma patients of the Advanced Imaging for Glaucoma study were selected for analysis if they had 9 completed visits. Confirmed rapid significant progression (CRSP) of VF was defined as a significant (P < 0.05) negative VF index (VFI) slope of -1%/year or a mean deviation slope of -0.5 dB/year, confirmed at 2 consecutive follow-up visits. Slow progression was defined as VFI slope greater than -0.5%/year or a mean deviation slope of -0.25 dB/year. Fourier-domain optical coherence tomography (FD-OCT) measured optic disc, peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) thicknesses. Logistic regression was used to identify baseline predictors for CRSP and slow progression. Linear regression was used to identify baseline predictors for the VFI and mean deviation slope. Eyes (n = 150) of 103 participants were included. Slow progression was observed in 80 eyes (53.3%) and CRSP in 23 eyes (15.3%). Larger NFL and GCC baseline focal loss volume (FLV), thinner central corneal thickness, and lower VFI were significant (P < 0.05) baseline predic...Continue Reading

References

Nov 26, 1999·Ophthalmology·M C LeskeB Bengtsson
Oct 9, 2002·Archives of Ophthalmology·Anders HeijlUNKNOWN Early Manifest Glaucoma Trial Group
Jan 14, 2003·Archives of Ophthalmology·M Cristina LeskeUNKNOWN Early Manifest Glaucoma Trial Group
May 27, 2003·Investigative Ophthalmology & Visual Science·Brenda W GillespieUNKNOWN CIGTS (Collaborative Initial Glaucoma Treatment Study) Study Group
Sep 8, 2004·Ophthalmology·Kouros Nouri-MahdaviUNKNOWN Advanced Glaucoma Intervention Study
Feb 21, 2006·The British Journal of Ophthalmology·H A Quigley, A T Broman
Nov 11, 2006·Ophthalmology·UNKNOWN Ocular Hypertension Treatment Study GroupMichael A Kass
Jul 14, 2007·Ophthalmology·M Cristina LeskeUNKNOWN EMGT Group
Nov 6, 2007·Ophthalmology·Ou TanUNKNOWN Advanced Imaging for Glaucoma Study Group
Dec 15, 2007·American Journal of Ophthalmology·Boel Bengtsson, Anders Heijl
Jan 24, 2008·The British Journal of Ophthalmology·B C ChauhanA Heijl
Oct 27, 2009·Ophthalmology·Anders HeijlUNKNOWN Early Manifest Glaucoma Trial Group
Feb 26, 2011·The British Journal of Ophthalmology·Giacomo SaviniMichele Carbonelli
Sep 29, 2011·Journal of Glaucoma·Harsha Laxmana RaoChandra S Garudadri
Mar 8, 2012·Investigative Ophthalmology & Visual Science·Carlos Gustavo De MoraesUNKNOWN Ocular Hypertension Treatment Study Group
Mar 27, 2012·Investigative Ophthalmology & Visual Science·Carlos Gustavo De MoraesJeffrey M Liebmann
Jun 30, 2012·Investigative Ophthalmology & Visual Science·David HuangUNKNOWN Advanced Imaging for Glaucoma Study-AIGS Group
Dec 13, 2012·Investigative Ophthalmology & Visual Science·Harsha L RaoChandra S Garudadri
Apr 9, 2013·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Sibel KocabeyogluMurat Irkec
Dec 3, 2014·American Journal of Ophthalmology·Phuc V LeUNKNOWN Advanced Imaging for Glaucoma Study Group
Nov 17, 2015·Investigative Ophthalmology & Visual Science·Azusa AkashiMakoto Nakamura
Dec 3, 2015·American Journal of Ophthalmology·Xinbo ZhangUNKNOWN Advanced Imaging for Glaucoma Study Group
Mar 22, 2016·Journal of Current Glaucoma Practice·Marina Cc SousaTiago S Prata
Sep 22, 2016·American Journal of Ophthalmology·Xinbo ZhangUNKNOWN Advanced Imaging for Glaucoma Study Group
Oct 25, 2016·Progress in Retinal and Eye Research·C Gustavo De MoraesLeonard A Levin

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Citations

Aug 28, 2019·Journal of Glaucoma·Mohammadreza AkbariMasoud Aghsaei Fard
Aug 22, 2020·Translational Vision Science & Technology·Francesca CappelliRoberta Ricciarelli
Aug 11, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Esther Arranz-MarquezAndreas Katsanos
Sep 26, 2020·Cellular Microbiology·Jessica B von PeinMatthew J Sweet
Jul 14, 2020·Progress in Retinal and Eye Research·Gala BeykinJeffrey L Goldberg
Apr 9, 2021·The British Journal of Ophthalmology·Fei LiLinda M Zangwill
Jun 11, 2021·Translational Vision Science & Technology·Ou TanDavid Huang
Dec 8, 2021·Acta Ophthalmologica·Ana Ortueta-OlartecoecheaPilar Tejada-Palacios

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