Predictive factors of early mortality after percutaneous endoscopic gastrostomy placement: The importance of C-reactive protein

Clinical Nutrition ESPEN
Mara BarbosaJose Cotter

Abstract

Percutaneous endoscopic gastrostomy (PEG) is considered one of the preferred routes for long-term enteral feeding. However, early mortality after PEG placement is high. We aimed at analyzing overall and early mortality in patients who underwent PEG insertion and at identifying risk factors of increased mortality after the procedure. Retrospective study which included patients who had a PEG insertion at our department between May 2007 and January 2013. Variables analyzed: demographic, Charlson's co-morbidity index, past aspiration pneumonia, indication for PEG, hemogram, ionogram, urea, creatinine, albumin and C-reactive protein (CRP). death. Kaplan-Meier survival analysis was used to calculate mortality after PEG placement. Predictive factors of overall mortality were identified by univariate and multivariate analysis and of 30-day, 90-day and 180-day mortality by logistic regression. The AUROC analysis for CRP levels was performed. Inclusion of 135 patients: 51.9% female, mean age of 73 ± 17 years, 90.4% with neurological dysphagia and 9.6% with tumors compromising oral intake. The median survival time was 272 days. The 30-day, 90-day and 180-day mortality was 0.14 ± 0.06 (95% CI 0.08-0.20), 0.29 ± 0.08 (95% CI 0.21-0.37) and ...Continue Reading

Citations

Jul 27, 2017·European Journal of Gastroenterology & Hepatology·Gonçalves T CúrdiaJosé Cotter
Nov 19, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·María Aurora Iturbide-CasasGuillermo Molina-Recio
Dec 13, 2019·Canadian Journal of Gastroenterology & Hepatology·Wisam SbeitTawfik Khoury

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