Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding

The Korean Journal of Internal Medicine
Yoo Jin LeeSeong Woo Jeon

Abstract

Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition. A prospective observational study was conducted at a single hospital between April 2010 and November 2012, and 336 patients with symptoms and signs of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics and endoscopic findings were reviewed to identify potential factors associated with 30-day mortality. Overall, 184 patients were included in the study (men, 79.3%; mean age, 59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age ≥ 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization were significant predictive factors of 30-day mortality. Comorbidity of DM or metastatic malignancy, age ≥ 65 years, and hemodynamic instability during hospitalization were predictors of 30-day mortality in patients with NVUGIB. These results will help guide the management of patients with this condition.

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Citations

Jun 22, 2017·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Soo-Han ChoKyoung Soo Lim
Sep 17, 2016·Journal of Clinical Gastroenterology·Ruiqi Chen, Chao You
Oct 17, 2019·World Journal of Clinical Cases·Daniela Cornelia LazărAdrian Goldiş
Jan 20, 2021·The American Journal of Emergency Medicine·Sung Jin BaeSun Hwa Lee

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