Predictive factors of small bowel patency in Crohn's disease patients

Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
Andreia AlbuquerqueGuilherme Macedo

Abstract

Patency capsule was developed to avoid small bowel video capsule endoscopy retention, namely in patients with Crohn's disease. To evaluate the predictive factors of small bowel patency in Crohn's disease patients. Retrospective analysis including 151 Crohn's disease patients submitted to patency capsule (Agile® Patency Capsule) from 2011 to 2012. Patients that excreted the intact patency capsule were classified as having a patent small bowel (without patency capsule retention), other patients were considered to have negative patency of the small bowel (patency capsule retention). Patients had a mean age of 41±14 years, 54% were female and 25% had been previously submitted to surgery. Stricturing disease was seen in 20% of cases and penetrating disease in 16% of cases. Left-sided colonic lesions and ileal strictures were observed at colonoscopy in 13% and 9% of patients, respectively. In our sample, 28% of patients had negative patency of the small bowel (patency capsule retention). In multivariate analysis, independent factors that were associated with negative patency of the small bowel in Crohn's disease patients were stricturing (OR 10.16, p < 0.001) and penetrating phenotypes (OR 11.73, p = 0.001), left-sided colonic lesion...Continue Reading

References

Sep 1, 1992·The British Journal of Surgery·A L SheehanN A Shepherd
Oct 19, 2000·Virchows Archiv : an International Journal of Pathology·G OberhuberC Gasche
Jul 20, 2002·Inflammatory Bowel Diseases·Jacques CosnesJean-Pierre Gendre
Aug 12, 2003·Inflammatory Bowel Diseases·Matthew A Ciorba, Chandra Prakash
Sep 29, 2005·Endoscopy·D CaveUNKNOWN ICCE
Mar 11, 2006·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C SignorelliR de Franchis
Jul 20, 2006·The American Journal of Gastroenterology·Adam S CheifetzBlair S Lewis
Oct 3, 2007·Gastrointestinal Endoscopy·Akira FukumotoKentaro Sugano
May 23, 2008·Journal of Clinical Gastroenterology·Cristiano SpadaGuido Costamagna
Jul 5, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·L BianconeF Pallone
Sep 12, 2008·World Journal of Gastroenterology : WJG·Angel Caunedo-AlvarezJuan-M Herrerias-Gutierrez
Dec 3, 2010·Journal of Crohn's & Colitis·Gert Van AsscheUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Dec 3, 2010·Journal of Crohn's & Colitis·Gert Van AsscheUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Jan 24, 2012·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Anthony BuissonLaurent Peyrin-Biroulet
Apr 30, 2013·Gut·Florian RiederWilliam J Sandborn
Nov 5, 2013·Journal of Crohn's & Colitis·Vito AnneseUNKNOWN European Crohn's and Colitis Organisation

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Citations

Apr 26, 2019·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Alba Cebrián GarcíaIgnacio Fernández-Urién Sainz
Mar 17, 2020·Techniques in Coloproctology·G PellinoUNKNOWN Italian Society of Colorectal Surgery SICCR

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