Predictive model for postoperative delirium in cardiac surgical patients

Seminars in Cardiothoracic and Vascular Anesthesia
Anoushka AfonsoBrigid Flynn

Abstract

Delirium is a common complication following cardiac surgery, and the predictors of delirium remain unclear. The authors performed a prospective observational analysis to develop a predictive model for postoperative delirium using demographic and procedural parameters. A total of 112 adult postoperative cardiac surgical patients were evaluated twice daily for delirium using the Richmond Agitation-Sedation Scale (RASS) and Confusion Assessment Model for the ICU (CAM-ICU). The incidence of delirium was 34% (n = 38). Increased age (odds ratio [OR] = 2.5; 95% confidence interval [CI] = 1.6-3.9; P < .0001, per 10 years) and increased duration of surgery (OR = 1.3; 95% CI = 1.1-1.5; P = .0002, per 30 minutes) were independently associated with postoperative delirium. Gender, BMI, diabetes mellitus, preoperative ejection fraction, surgery type, length of cardiopulmonary bypass, intraoperative blood component administration, Acute Physiology and Chronic Health Evaluation II score, Sequential Organ Failure Assessment score, and Charlson Comorbidity Index, were not independently associated with postoperative delirium.

References

Feb 23, 1990·JAMA : the Journal of the American Medical Association·J FrancisW N Kapoor
Jun 1, 1988·Journal of the American Geriatrics Society·Y GustafsonB Winblad
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Jan 12, 1994·JAMA : the Journal of the American Medical Association·E R MarcantonioR Poss
Jun 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·T WalzerC W Wallesch
Dec 22, 1999·Age and Ageing·K RockwoodJ Fisk
Mar 4, 2000·Stroke; a Journal of Cerebral Circulation·W R BrownJ W Hammon
Feb 13, 2001·Psychosomatics·K FrancoD Bronson
Feb 15, 2001·The New England Journal of Medicine·M F NewmanUNKNOWN Neurological Outcome Research Group and the Cardiothoracic Anesthesiology Research Endeavors Investigators
Mar 30, 2001·The Journal of Thoracic and Cardiovascular Surgery·M A BorgerC M Feindel
Jan 18, 2002·Intensive Care Medicine·E W ElyS K Inouye
Feb 6, 2002·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·UNKNOWN American College of Critical Care Medicine of the Society of Critical Care Medicine, American Society of Health-System Pharm
Mar 21, 2002·Critical Care Medicine·Judith JacobiUNKNOWN Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), America
Mar 21, 2002·JAMA : the Journal of the American Medical Association·Diederik Van DijkUNKNOWN Octopus Study Group
Nov 8, 2002·American Journal of Respiratory and Critical Care Medicine·Curtis N SesslerR K Elswick
Mar 11, 1965·The New England Journal of Medicine·S GILMAN
Jan 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·Jan BuceriusFriedrich W Mohr
Apr 9, 2004·Critical Care Medicine·Eric B MilbrandtE Wesley Ely
Apr 15, 2004·JAMA : the Journal of the American Medical Association·E Wesley ElyRobert S Dittus
Sep 3, 2005·Critical Care : the Official Journal of the Critical Care Forum·Jason W W ThomasonE Wesley Ely
Feb 22, 2007·JAMA : the Journal of the American Medical Association·Diederik van DijkUNKNOWN Octopus Study Group
Apr 3, 2007·Intensive Care Medicine·John W DevlinRichard R Riker
May 10, 2007·Scandinavian Cardiovascular Journal : SCJ·Ieva NorkieneGiedrius Uzdavinys
Jan 16, 2008·Archives of Internal Medicine·Douglas L LeslieSharon K Inouye
Mar 4, 2008·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·James L RudolphEdward R Marcantonio
Jul 8, 2008·British Journal of Anaesthesia·F M RadtkeC D Spies
Nov 22, 2008·The Annals of Thoracic Surgery·Sandra KosterJob van der Palen
Apr 22, 2009·The Annals of Thoracic Surgery·Sandra KosterJob van der Palen

❮ Previous
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Citations

Feb 22, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Robbert C BakkerAd J J C Bogers
Sep 21, 2011·Critical Care : the Official Journal of the Critical Care Forum·Julika SchoenKlaus-Ulrich Berger
Oct 13, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Alexa HollingerLuzius A Steiner
Aug 21, 2013·Psychosomatics·Andreas Baranyi, Hans-Bernd Rothenhäusler
Apr 27, 2013·Medical Hypotheses·Aibek E MirrakhimovMadan M Kwatra
Dec 20, 2011·Cirugía española·Nicolás Martínez-VelillaRafael Sánchez-Ostiz
Dec 28, 2011·The Annals of Thoracic Surgery·Billie-Jean MartinRoger J F Baskett
Jul 12, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Melanie StranskyBenedikt Trabold
Dec 2, 2015·Clinical Therapeutics·Charles H BrownCharles W Hogue
Dec 15, 2015·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Akiko ShioiriToru Nishikawa
Jul 13, 2012·Journal of Cardiac Surgery·Yiyun LinZhinong Wang
Jul 13, 2011·The Mount Sinai Journal of Medicine, New York·Dennis M Popeo
Sep 24, 2015·Critical Care : the Official Journal of the Critical Care Forum·Alex Nc GosseltIrene J Zaal
Apr 8, 2016·Annals of Cardiac Anaesthesia·Adam S EvansHarish Ramakrishna
Oct 24, 2013·Interactive Cardiovascular and Thoracic Surgery·Senol Yavuz
May 1, 2012·International Journal of Nursing Studies·Priscilla G TaipaleJaime Gallaher
Feb 12, 2017·European Journal of Anaesthesiology·César AldecoaClaudia D Spies
Dec 16, 2011·Perfusion·J Andrejaitiene, E Sirvinskas
Dec 30, 2017·BMC Geriatrics·Gizat M KassieElizabeth E Roughead
Mar 29, 2018·Minerva anestesiologica·Jeroen HermanidesFederico Bilotta
Oct 6, 2017·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Miarca Ten BroekeJob van der Palen
Jul 26, 2011·European Journal of Anaesthesiology·Luzius A Steiner
Sep 29, 2019·JMIR Medical Informatics·Hani Nabeel MuftiSyed Sibte Raza Abidi
Jan 18, 2020·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Hailin XingGuozhu Xie
Jan 13, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Włodzimierz PłotekRegina Samborska
Mar 22, 2019·BMC Anesthesiology·Onuma ChaiwatChayanan Thanakiattiwibun
Aug 23, 2017·Brain and Behavior·Ying ZhuJian-Rong Wang
Sep 8, 2020·Critical Care Clinics·Rohan SanjanwalaRakesh C Arora
Sep 3, 2021·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Hsiao-Wei ChengAi-Fu Chiou

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