Predictive Modeling of Influenza Shows the Promise of Applied Evolutionary Biology.

Trends in Microbiology
Dylan H MorrisJohn W McCauley

Abstract

Seasonal influenza is controlled through vaccination campaigns. Evolution of influenza virus antigens means that vaccines must be updated to match novel strains, and vaccine effectiveness depends on the ability of scientists to predict nearly a year in advance which influenza variants will dominate in upcoming seasons. In this review, we highlight a promising new surveillance tool: predictive models. Based on data-sharing and close collaboration between the World Health Organization and academic scientists, these models use surveillance data to make quantitative predictions regarding influenza evolution. Predictive models demonstrate the potential of applied evolutionary biology to improve public health and disease control. We review the state of influenza predictive modeling and discuss next steps and recommendations to ensure that these models deliver upon their considerable biomedical promise.

References

Sep 1, 1970·Archives of Environmental Health· Fazekas de St Groth
Dec 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Julia R Gog, Bryan T Grenfell
Aug 26, 2003·Physical Review Letters·Michael W Deem, Ha Youn Lee
Jan 17, 2004·Science·Bryan T GrenfellEdward C Holmes
Jan 5, 2005·Vaccine·Enrique T Muñoz, Michael W Deem
Feb 8, 2006·Vaccine·Vishal GuptaMichael W Deem
Mar 3, 2006·PLoS Medicine·Cécile ViboudLone Simonsen
Jul 5, 2006·Molecular Biology and Evolution·Yoshiyuki Suzuki
Dec 5, 2006·PLoS Pathogens·Martha I NelsonEdward C Holmes
Jan 31, 2007·Nature Reviews. Genetics·Martha I Nelson, Edward C Holmes
Mar 31, 2007·Proceedings of the National Academy of Sciences of the United States of America·Arthur Chun-Chieh ShihWen-Hsiung Li
Jun 5, 2007·Vaccine·Noelle-Angelique M MolinariCarolyn B Bridges
Aug 22, 2007·PLoS Computational Biology·Sergey KryazhimskiyJonathan Dushoff
Oct 19, 2007·PLoS Pathogens·Martha I NelsonEdward C Holmes
Oct 19, 2007·Journal of Virology·Yiming BaoDavid Lipman
Oct 27, 2009·PLoS Computational Biology·Edward C Holmes, Bryan T Grenfell
Nov 11, 2009·Science·Andrew W ParkBryan T Grenfell
Dec 17, 2009·Vaccine·Ian G BarrUNKNOWN Writing Committee of the World Health Organization Consultation on Northern Hemisphere Influenza Vaccine Composition for 200
Nov 26, 2010·Environmental Health Perspectives·James TameriusWladimir J Alonso
Mar 11, 2011·PLoS Genetics·Sergey KryazhimskiyJoshua B Plotkin
Mar 19, 2011·Molecular Biology and Evolution·Samir BhattOliver G Pybus
Apr 12, 2011·Influenza and Other Respiratory Viruses·Wilfred Ndifon
Jun 23, 2011·Expert Review of Anti-infective Therapy·Jacqueline M KatzXiyan Xu
Oct 27, 2011·PloS One·Kimihito ItoAyato Takada
Jan 20, 2012·Nature·Mel Greaves, Carlo C Maley
Feb 11, 2012·Proceedings of the National Academy of Sciences of the United States of America·Nimalan ArinaminpathyBryan T Grenfell
Feb 15, 2012·Proceedings of the National Academy of Sciences of the United States of America·Benjamin D GreenbaumRaul Rabadan
Apr 26, 2012·PLoS Computational Biology·Lars Steinbrück, Alice Carolyn McHardy
Jul 26, 2012·PLoS Pathogens·Justin LesslerDerek A T Cummings
Aug 2, 2012·Genetics·Natalja Strelkowa, Michael Lässig
Aug 25, 2012·Vaccine·Alexander I KlimovUNKNOWN Writing Committee of the World Health Organization Consultation on Southern Hemisphere Influenza Vaccine Composition for 201
Jan 10, 2013·PLoS Pathogens·Christopher J R Illingworth, Ville Mustonen
Jan 19, 2013·Annual Review of Medicine·Natalie Pica, Peter Palese
Feb 6, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Paul S WikramaratnaSunetra Gupta
Feb 6, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Austin G MeyerClaus O Wilke
Jul 4, 2013·MBio·Hailiang SunXiu-Feng Wan
Jul 17, 2013·The Journal of Experimental Medicine·Yang LiScott E Hensley
Sep 21, 2013·Scientific Reports·F TriaV Loreto
Jan 15, 2014·PLoS Genetics·Alexey D NeverovGeorgii A Bazykin

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Citations

May 4, 2018·Influenza and Other Respiratory Viruses·Alan J Hay, John W McCauley
Jan 27, 2018·Virology Journal·Giuseppe A SauttoTed M Ross
Jun 4, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lu YangPeter Andolfatto
Nov 2, 2019·Journal of Clinical Microbiology·Kuiama LewandowskiPhilippa C Matthews
Aug 24, 2018·Journal of Clinical Microbiology·Richard A Neher, Trevor Bedford
Jun 9, 2020·ELife·Michael J MinaBryan T Grenfell
Apr 8, 2020·Proceedings. Biological Sciences·Maryam HayatiCaroline Colijn
May 12, 2020·Annual Review of Virology·Sigrid GoumaScott E Hensley
Jun 29, 2018·Genome Medicine·Tommy T Lam, Oliver G Pybus
Sep 25, 2018·Frontiers in Immunology·Konstantinos VoskaridesGeorgios K Nikolopoulos
Aug 2, 2020·Proceedings of the National Academy of Sciences of the United States of America·Michael Lässig, Ville Mustonen
Aug 8, 2018·Viruses·Daniel M Lyons, Adam S Lauring
Oct 6, 2018·Science·Benjamin D DalzielBryan T Grenfell
Apr 20, 2019·Scientific Reports·Thorsten R KlingenAlice C McHardy
Oct 23, 2020·PLoS Biology·Taj AzarianWilliam P Hanage
Mar 23, 2021·Molecular Biology and Evolution·Pierre Barrat-CharlaixRichard A Neher
Jan 29, 2020·Cold Spring Harbor Perspectives in Medicine·Huong Q McLean, Edward A Belongia
Jun 3, 2021·Nature Reviews. Microbiology·William T HarveyDavid L Robertson
Jun 30, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jacopo MarchiThierry Mora

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