Predictive value of hormonal profiles before stimulation for in vitro fertilization

Fertility and Sterility
P FénichelM Harter

Abstract

Ovarian responses to stimulation for in vitro fertilization by clomiphene citrate menotropins have been correlated to the hormonal profiles determined during spontaneous cycles. The authors found 80% of high plasmatic luteinizing hormone (LH) and/or androgens levels associated with an inappropriated response: premature LH surge, multifollicular ovarian response, or dissociated cystic response, versus only 11% with appropriated responses. High plasmatic follicle-stimulating hormone existed in 71% of the no response group. Detryptoréline, a luteinizing hormone-releasing hormone agonist associated with menotropins, in a "short procedure" maintained the adequate responses and suppressed premature LH surges. The no response group was moderately improved, as were multifollicular and dissociated cystic response groups. Hormonal profiles could be useful predictive factors of the ovarian response for adaptation on the first procedure of stimulation.

Citations

Feb 1, 1993·Journal of Assisted Reproduction and Genetics·F OlivennesR Frydman
Sep 17, 2009·Archives of Gynecology and Obstetrics·Tevfik Yoldemir, Ian S Fraser
Nov 1, 1990·Molecular Reproduction and Development·D P WolfR L Stouffer
Dec 1, 1994·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Z Ben-RafaelD Feldberg
Feb 1, 1995·American Journal of Reproductive Immunology : AJRI·P FenichelB L Hsi

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