Predictive value of lymphocyte to monocyte ratio and monocyte to high-density lipoprotein ratio for acute deep vein thrombosis after total joint arthroplasty: a retrospective study

Journal of Orthopaedic Surgery and Research
Xiaobo ZhuQing Jiang

Abstract

Deep vein thrombosis (DVT) is one of the most dangerous complications of total joint arthroplasty (TJA). Systemic inflammation has proved to have a great contribution to thrombosis and has been considered as a risk factor for DVT recently. The lymphocyte to monocyte ratio (LMR) and monocyte to high-density lipoprotein (HDL) ratio (MHR) are two biomarkers used widely for systemic inflammation. This study aims to find out the potential predictive value of LMR and MHR for DVT after TJA. A total of 853 patients who underwent primary TJA were finally included in this retrospective study. Acute DVT after TJA was evaluated by venography. Preoperative and postoperative LMR and MHR were calculated according to the blood routine test and blood biochemistry test. The association between LMR or MHR and DVT and their predictive value were evaluated by multiple logistic regression analysis and ROC curve respectively. Totally, 126 patients (14.8%) were diagnosed with DVT by venography. Patients with DVT had a significantly higher level of preoperative MHR (P < 0.001) and postoperative MHR (P < 0.001), along with a significantly lower level of preoperative LMR (P < 0.001) and postoperative LMR (P < 0.001). Multiple logistic regression indicate...Continue Reading

References

May 22, 1990·Biochimica Et Biophysica Acta·S ParthasarathyL G Fong
Feb 1, 1972·Archives of Surgery·K Rabinov, S Paulin
Oct 9, 2004·Journal of Vascular Surgery·Elisabeth KriegerRenate Koppensteiner
Aug 9, 2005·Archives of Gerontology and Geriatrics·B Caracciolo, S Giaquinto
Jul 3, 2007·Clinical Orthopaedics and Related Research·Victoria BranderS David Stulberg
Oct 8, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·I BautmansT Mets
Oct 22, 2009·Clinical Orthopaedics and Related Research·Robert B BourneKory D J Charron
Mar 23, 2012·Thrombosis and Haemostasis·Y I G Vladimir TichelaarKarina Meijer
Jul 3, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Eftal Murat BakirciMahmut Acikel
Jul 12, 2014·Annals of Nutrition & Metabolism·Klara BelajThomas Gary
Sep 21, 2015·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Tyler BarkerG Lynn Rasmussen
Oct 20, 2015·World Journal of Gastroenterology : WJG·Ze-Xiao LinXiang-Yuan Wu
Apr 17, 2017·Clinical Colorectal Cancer·Sabrina RossiCarlo Barone
Apr 27, 2017·Journal of Clinical Lipidology·Roosmarijn F H LemmersMonique T Mulder
Jul 13, 2017·Stroke; a Journal of Cerebral Circulation·Aaron M GusdonSantosh B Murthy
Oct 17, 2017·Techniques in Vascular and Interventional Radiology·Nicholas J GiordanoChristopher Kabrhel
Apr 24, 2018·Revista española de anestesiología y reanimación·A F RibeiroC Dias

❮ Previous
Next ❯

Citations

Mar 22, 2020·International Journal of Molecular Sciences·J Matthew NicklasPeter K Henke
Jul 6, 2021·Journal of Clinical and Translational Hepatology·Jian-Bo HanYong-Xiang Yi

❮ Previous
Next ❯

Software Mentioned

MedCalc
SPSS

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.