Predictive value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for acute deep vein thrombosis after total joint arthroplasty: a retrospective study

Journal of Orthopaedic Surgery and Research
Chen YaoDongquan Shi

Abstract

Deep vein thrombosis (DVT) is a common and severe complication of total joint arthroplasty (TJA). Inflammation has been proved to play a role in DVT. The neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) are biomarkers for systemic inflammation. The aim of the study is to investigate the predictive value of NLR and PLR for acute TJA-induced DVT. A total of 773 patients who underwent primary TJA in our hospital were included in this retrospective study. Venography was performed routinely after the surgery to define acute DVT. NLR and PLR before and after operation were calculated according to the blood routine test. Multiple logistic regression analyses and ROC curve analyses were performed to assess the association of NLR and PLR with TJA-induced DVT. One hundred twenty out of 773 patients (15.5%) were diagnosed with DVT by venography. In patients with DVT, preoperative NLR (P = 0.030) and postoperative NLR (P = 0.015) were significantly higher but postoperative PLR (P = 0.002) was significantly lower. Multiple logistic regression analyses indicated that age (OR = 1.05, P < 0.005), gender (OR = 0.47, P = 0.005), BMI (OR = 1.06, P < 0.014), preoperative NLR (OR = 1.11, P < 0.035), postoperative NLR ...Continue Reading

References

Apr 23, 2004·Journal of Thrombosis and Haemostasis : JTH·P H Reitsma, F R Rosendaal
Feb 28, 2006·Thrombosis Research·Edelmiro ReganonJusto Aznar
May 24, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Angela PapaFranca Cocci
May 15, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Jeppe ZachoBørge G Nordestgaard
Apr 25, 2012·Journal of Thrombosis and Thrombolysis·Huacheng HouQing Jiang
Jul 3, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Eftal Murat BakirciMahmut Acikel
Sep 13, 2013·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Zhihong XuQing Jiang
Aug 17, 2014·Journal of Critical Care·Daniel J McIlroyZsolt J Balogh
Aug 16, 2015·Seminars in Thrombosis and Hemostasis·Mostafa A AlbayatiAlberto Smith
Sep 21, 2015·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Tyler BarkerG Lynn Rasmussen
Mar 2, 2016·Seminars in Thrombosis and Hemostasis·Silvia Montoro-GarcíaThomas Thiele
Jul 26, 2016·Frontiers in Immunology·Andrew S KimballPeter K Henke

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Citations

Sep 12, 2019·Journal of Clinical Laboratory Analysis·Raymond FarahRola Khamisy-Farah
Sep 21, 2018·Molecular and Clinical Oncology·Yusuke KumamotoMasahiko Watanabe
Sep 30, 2020·International Orthopaedics·Zhicong WangYuehong Liu
Feb 3, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Peter PoredosJawed Fareed
Sep 29, 2021·Indian Journal of Ophthalmology·Ali H ReyhanŞerife Şule Çınar

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Methods Mentioned

BETA
total hip arhroplasty
dissection

Software Mentioned

SPSS

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