Predictive value of non-automated spermatic parameters and automated kinetic parameters on cleavage rate in fertilization in vitro

Gynécologie, obstétrique & fertilité
A ChocatA Sauvalle

Abstract

The aim of this work was to determine retrospectively in 114 couples the predictive value of semen analysis for the in vitro fertilization (IVF) outcome when sperm evaluation before IVF was assessed by either conventional parameters or a Hamilton-Thorne automated motility analyser. A backward logistic regression analysis was used to study the relative contribution of each conventional or computerized parameter. Computerized sperm values were the worst index for predicting oocyte fertilization. However a tight relationship between morphology and cleavage ratio was observed. Using ROC analysis, under a 18% threshold, cleavage failure was noted in 71% of couples undergoing an IVF program. This study indicates that morphology is the best parameter for predicting cleavage failure.

Citations

Jan 14, 2010·Folia Histochemica Et Cytobiologica·I Galeraud-DenisS Carreau
Jun 3, 2014·Reproductive Biology and Endocrinology : RB&E·Ashok AgarwalRakesh Sharma
May 29, 2009·Genetic Testing and Molecular Biomarkers·Ying ChenHong Li

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