PMID: 6129473Dec 18, 1982Paper

Predictive value of surveillance skin cultures in total-parenteral-nutrition-related infection

Lancet
D R SnydmanL K Perry

Abstract

To assess the importance of skin flora in the pathogenesis of infection complicating total parenteral nutrition and the predictive value of positive skin cultures for the development of infection 54 patients, who received 59 courses of total parenteral nutrition, were followed up. Three times per week, at the time of dressing and line changes, the skin at the site of insertion of the cannula was swabbed for culture. Results of skin cultures were compared with results of semiquantitative culture of the proximal intravascular portion of the cannula. Infected patients were defined as those having cannula cultures with greater than or equal to 15 colonies or those with primary septicaemia. 21 of 59 courses (36%) were associated with positive skin cultures; 14 of these 21 courses were associated with cannula infection, 2 with bacteraemia or fungaemia, and 12 with local infection. 38 of 59 (64%) courses had sterile skin cultures; in none of these 38 patients did infection develop (p less than 0.001). Skin colonisation was associated with otherwise unexplained fever (11 of 21 with positive skin culture versus 5 of 38 with negative skin culture, p less than 0.001), inflammation at the insertion site (13 of 21 versus 10 of 38, p less th...Continue Reading

Citations

Feb 1, 1995·Intensive Care Medicine·C R ReedB A Phelan
May 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J A CapdevilaJ M Martínez-Vázquez
Apr 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·N C WeightmanA Oakhill
Sep 17, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·L LaurenziE Arcuri
Aug 1, 1989·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·B Lee, R W Chang
Oct 1, 1988·Baillière's Clinical Gastroenterology·A J Sim
Apr 23, 1983·Lancet·D R Snydman
Feb 4, 1998·Critical Care Clinics·G A Bergen, J F Toney
Jun 29, 2000·Journal of the American College of Surgeons·S J PelletierR G Sawyer
Feb 20, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·M MoradoF Hernandez-Navarro
Apr 5, 1990·The New England Journal of Medicine·M S KlempnerM B Atkins
Oct 8, 1992·The New England Journal of Medicine·D K CobbB M Farr
Sep 11, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D K WarrenV J Fraser
Sep 21, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A B CronquistE L Larson
Feb 1, 1988·Revue de l'infirmière·Y Domart
Sep 1, 1983·Archives of Disease in Childhood·M M Placzek, A Whitelaw
May 1, 1986·Archives of Disease in Childhood·H MactierP A Raine
Jul 1, 1992·Archives of Disease in Childhood·N KeyworthK T Holland
Sep 1, 1993·Archives of Disease in Childhood·I MalathiN Marlow
Sep 1, 1986·Journal of Clinical Pathology·N C WeightmanD C Speller
Jan 25, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter J PronovostJohn A Jernigan
Apr 11, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·A LodhaA M Moore
Dec 4, 2003·Journal of Advanced Nursing·Donna GilliesRobbie Gunning
Jul 3, 2008·International Wound Journal·Piyush Durani, David Leaper
Aug 1, 1989·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J J BodyF Meunier
Jun 1, 1995·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·B Messing
Nov 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·W W Williams
Oct 1, 1988·The Journal of Hospital Infection·S T FanK K Wong
Sep 28, 2007·The Lancet Infectious Diseases·Issam RaadDennis Maki
Sep 1, 1991·The Journal of Hospital Infection·R L Hill, M W Casewell
Apr 1, 1991·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·S Curtas, K Tramposch
Mar 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·Y InoueA Okada
Jul 8, 2000·JPEN. Journal of Parenteral and Enteral Nutrition·J FortúnA Guerrero
Mar 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·J H Chuang, S F Chuang
Nov 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·Y InoueA Okada
Sep 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·L MukauM E McGuire
Jul 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·F BozzettiL Callegari
Jul 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·R H MulloyM L Russell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.