Predictor factors for the development of arterial hypertension following heart transplantation

Clinical Transplantation
Ignacio J Sánchez-LázaroA Salvador

Abstract

Up to 95% of the patients with heart transplantation (HT) suffer from arterial hypertension (AHT). The development of de novo AHT after HT has not been greatly studied. To identify the predictor variables for the development of de novo AHT after HT. We retrospectively studied 253 patients with HT and who did not previously have AHT. We excluded cases of early mortality, re-transplants and combined transplants. We considered AHT as the constant need to take anti-hypertensive drugs to maintain blood pressure < 140/90 mmHg. We studied all the variables relating to recipient, donor, surgical procedure, immunosuppression and follow-up. The statistics used were the Student's t-test, chi-square statistic and a logistic regression analysis. Of the 253 patients, 109 (43%) developed AHT. The variables associated with more prevalent AHT were male recipient/donor, idiopathic dilated cardiomyopathy (IDCM) as cause of HT, having been a smoker as well as renal deterioration (RD) and hypercholesterolemia after HT. The multivariate analysis found smoking prior to the HT and hypercholesterolemia during follow-up as independent risk factors and urgent HT as a protective variable. AHT after HT is frequent. The variables associated in our populatio...Continue Reading

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Citations

Jul 21, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Maria Rosa CostanzoUNKNOWN International Society of Heart and Lung Transplantation Guidelines
Jul 25, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Luis Martínez-DolzJose Anastasio Montero
Feb 20, 2021·Transplantation Reviews·Guilherme Veiga GuimarãesEmmanuel Gomes Ciolac

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