Predictors and long-term outcome in Greek adults with juvenile idiopathic arthritis: a 17-year continuous follow-up study

Rheumatology
Despoina DimopoulouAlexandros Garyfallos

Abstract

To describe the disease characteristics, continuous course and long-term outcome and to evaluate predictors of outcome in JIA in Greece. We performed a retrospective cohort analysis of 17 years' prospective data on JIA. Outcome assessment included radiographic (modified Sharp-van der Heidje score), articular and extra-articular damage (Juvenile Arthritis Damage Index), functional ability (HAQ Disability Index), and the cumulative percentage time spent in a state of active disease and also in clinical remission off medication (CR) (according to Wallace's criteria). One hundred and two (72 females) patients under regular follow-up were enrolled. The disease age of onset [mean (SD)] was 7.7 (4) years, the interval from onset to last visit was 17.2 (6.7) years and the patients' current age was 25 (5.9) years. At the last follow-up visit, 53 patients (52%) had disease activity, while 23.5% were in CR. The cumulative percentage time spent in a state of active disease and CR over the disease course was 52.6 and 17.8%, respectively. Polyarticular subtype of onset and longer disease activity during the first 5 years were independent predictors of worse outcome. Additional telephone-based interviews of 205 former JIA patients who had bee...Continue Reading

References

Feb 1, 1992·Annals of the Rheumatic Diseases·D M van der HeijdeL B van de Putte
Mar 21, 2000·Rheumatology·M Zak, F K Pedersen
Oct 2, 2002·Arthritis and Rheumatism·Kirsten MindenAngela Zink
Oct 29, 2005·Arthritis and Rheumatism·Carol A WallaceEdward H Giannini
Jan 30, 2008·Pediatrics·Øystein Rolandsen RiiseBerit Flatø
May 1, 2009·Arthritis and Rheumatism·Alessandro ConsolaroUNKNOWN Paediatric Rheumatology International Trials Organisation
Feb 17, 2010·The Journal of Rheumatology·Arthur KavanaughShao-Lee Lin
Nov 12, 2010·Annals of the Rheumatic Diseases·Pedro MachadoUNKNOWN Assessment of SpondyloArthritis international Society
May 12, 2011·Arthritis and Rheumatism·Ellen NordalUNKNOWN Nordic Study Group of Pediatric Rheumatology
Jul 1, 2011·Arthritis Care & Research·Carol A WallaceUNKNOWN Paediatric Rheumatology International Trials Organisation
Jan 11, 2012·Arthritis and Rheumatism·Alessandro ConsolaroUNKNOWN Paediatric Rheumatology International Trials Organization

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Citations

Aug 3, 2018·Scandinavian Journal of Rheumatology·N J MarsT Sokka-Isler
May 16, 2019·Current Opinion in Rheumatology·Jaime GuzmanThomas Loughin
Jun 23, 2018·Rheumatology·Evert H Pieter van DijkhuizenAlberto Martini
Oct 12, 2018·Arthritis Research & Therapy·Juan José Bethencourt BauteUNKNOWN BIOBADASER study group
Sep 25, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Semanur OzdelMehmet Bulbul
Jul 2, 2021·Pediatric Rheumatology Online Journal·Sirinthip KittivisuitSoamarat Vilaiyuk
Jan 7, 2022·International Journal of Rheumatic Diseases·Kai Liang TehThaschawee Arkachaisri

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