Abstract
Asian Indians develop type 2 diabetes mellitus (T2DM) much earlier as compared to White Caucasians, due to unique phenotypic and genetic architecture. Periodontitis in T2DM patients is often a neglected clinical feature. This study was conducted to derive predictor variables for gingival index in middle-aged Asian Indians with T2DM in a semiurban population of Dravidian ethnicity from Tamil Nadu, India. T2DM patients (n = 232, mean age: 50.6 ± 10.4 years) with periodontitis (n = 123, mean age: 54.3 ± 2.4 years) and without periodontitis (n = 109, mean age: 55.2 ± 3.1 years) were recruited between 2014 and 2016 by purposive sampling method. Dental examinations for pocket depth (PD) and clinical attachment level (CAL) were performed and gingival index was calculated. Fasting venous blood samples were analysed for measures of glycaemia and cholesterol. Significant positive correlation (p < 0.01) was observed for gingival index with glycosylated haemoglobin (HbA1c), pocket depth, presence of T2DM, and clinical attachment level. Stepwise multiple linear regression analysis derived increased pocket depth (p < 0.01), elevated HbA1c (p < 0.01), clinical attachment level (p < 0.01), and presence of diabetes (p < 0.01) as significant pre...Continue Reading
References
Mar 15, 2005·Glycobiology·Ravichandran RamasamyAnn Marie Schmidt
Nov 17, 2006·Journal of Epidemiology and Community Health·Sarah WamalaGunnel Boström
Jan 30, 2007·Diabetes Care·Wendy A ShultisRobert G Nelson
May 10, 2007·Oral Microbiology and Immunology·J HintaoG Dahlen
Mar 26, 2008·Circulation·Thomas DietrichRaul I Garcia
Apr 9, 2008·Diabetes Care·Ryan T DemmerMoïse Desvarieux
Jul 21, 2009·Journal of Human Evolution·Steven E ChurchillBrittany R Warren
Nov 8, 2011·Diabetologia·P M PreshawR Taylor
Apr 19, 2012·Journal of Periodontology·A R PradeepMinal Kumari
Sep 29, 2012·Journal of Periodontal Research·A ZizziG Lucarini
Dec 12, 2012·Journal of Oral Science·Ashish Aggarwal, Sunil R Panat
Jul 13, 2013·British Dental Journal·R S Levine
Nov 8, 2013·BMC Oral Health·Eun-Kyong KimHee-Kyung Lee
Jul 1, 2014·Journal of Global Health·Arsalan CheemaKit Yee Chan
Sep 10, 2014·Journal of Clinical Periodontology·Ira B LamsterEvanthia Lalla
Apr 11, 2015·International Journal of Oral Science·Ying-Ying WuDana T Graves
Jul 27, 2015·BMC Oral Health·Hasaan G MohamedManal Mustafa
Apr 27, 2016·PloS One·Atsushi MiyawakiYasuki Kobayashi
May 10, 2016·Endocrine Reviews·Alexandra Kautzky-WillerGiovanni Pacini
May 18, 2016·Journal of Clinical and Diagnostic Research : JCDR·Vidya S PatilPraveenchandra Kangokar
Sep 3, 2016·Biomedical Reports·Pengyu HanJie Yang
Jan 5, 2017·Frontiers of Medicine·Palka Kaur KhanujaShikha Tewari