Predictors for Haemophilus influenzae colonization, antibiotic resistance and for sharing an identical isolate among children attending 16 licensed day-care centers in Michigan

The Pediatric Infectious Disease Journal
Cibele Barbosa-CesnikB Foxman

Abstract

Nontypable Haemophilus influenzae is an important cause of otitis media in children. Children attending day-care centers are at an increased risk for nontypable H. influenzae colonization and otitis media. We describe the prevalence of nontypable H. influenzae colonization, antibiotic resistance and predictors for colonization and sharing an identical isolate with at least 1 other child in the same day-care centers among children attending 16 day-care centers. Throat swabs of 198 children < 3 years old attending 16 day-care centers were cultured for H. influenzae. Day-care center directors and parents completed risk factors questionnaires. Nontypable H. influenzae isolates were screened for antibiotic resistance and genotyped. Statistics were performed using SAS software (SAS Institute, Inc., Cary, NC). We isolated 179 unique nontypable H. influenzae strains from 127 participants. Colonization ranged from 0% to 95% among day-care centers. As individual factors, exposure to tobacco smoke was associated with colonization (P = 0.05), and racial self-identifications as "other" (nonwhite, nonblack) was protective (P = 0.035), whereas as "black" was protective for sharing (P = 0.03). Pacifier use was associated with sharing (P = 0.04...Continue Reading

References

Oct 1, 1979·Infection and Immunity·V Fainstein, D M Musher
Jun 1, 1992·The Journal of Infectious Diseases·G AnianssonC Svanborg
Jun 1, 1984·The Journal of Pediatrics·C D MarchantS E Kinney
Sep 1, 1983·Infection and Immunity·S S LongK L McGowan
Jun 1, 1996·American Journal of Epidemiology·O P AlhoH Oja
Jun 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M UhariM Niemelä
Jun 2, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D FontanalsF Sanchez
Feb 13, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D TalonJ M Estavoyer
Dec 6, 2001·The Pediatric Infectious Disease Journal·J RaymondP Berche
Apr 19, 2003·Journal of Clinical Microbiology·Henri DabernatPierre Dellamonica
Apr 16, 2003·Archives of Pediatrics & Adolescent Medicine·Jennifer F FriedmanJonathan A Finkelstein
Oct 22, 2003·The Pediatric Infectious Disease Journal·Michael R Jacobs
Jan 27, 2004·The Pediatric Infectious Disease Journal·Rand S FarjoJanet R Gilsdorf

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Citations

Dec 6, 2008·The Pediatric Infectious Disease Journal·Timothy F MurphyStephen I Pelton
Nov 5, 2011·The Pediatric Infectious Disease Journal·Sandra K SchumacherStephen I Pelton
Jan 11, 2008·Journal of Clinical Microbiology·Koichi HashidaHideaki Suzuki
Apr 11, 2014·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Carmen PuigCarmen Ardanuy
Mar 24, 2009·International Journal of Pediatric Otorhinolaryngology·K TanakaJ Yano
Nov 1, 2015·Memórias do Instituto Oswaldo Cruz·Rosemeire Cobo ZanellaAna Freitas Ribeiro
Jun 29, 2011·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Keisuke SunakawaSatoshi Iwata
May 5, 2017·The Pediatric Infectious Disease Journal·María Del Mar Ortiz-RomeroUNKNOWN Collaborators of Study Group of Infectious Diseases in the Child in Cartagena
Dec 19, 2018·Proceedings of the National Academy of Sciences of the United States of America·David A Relman, Marc Lipsitch
Apr 18, 2020·The Pediatric Infectious Disease Journal·Nicole L MessinaNigel Curtis
Dec 21, 2019·JAMA : the Journal of the American Medical Association·Lauren F CollinsMonica M Farley
Nov 27, 2009·Journal of Clinical Microbiology·Ankie LebonAlex van Belkum

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