Predictors for postoperative renal function after open partial nephrectomy: including postoperative biomarkers

International Journal of Urology : Official Journal of the Japanese Urological Association
Toshio TakagiKazunari Tanabe

Abstract

To assess the predictors of postoperative renal insufficiency after open partial nephrectomy. A total of 195 patients who underwent open partial nephrectomy were the participants in this study. Patients with a decrease in the estimated glomerular filtration rate of >25% from baseline were evaluated on the basis of multiple factors including patient-specific, surgical, tumor and postoperative factors. Postoperative estimated glomerular filtration rate data were recorded between 3 and 6 months after surgery. Of the 195 patients, 18 (9%) had a decrease in estimated glomerular filtration rate of >25%. Percentage of preserved renal parenchyma (P = 0.0078), nearness of tumor to renal sinus (P = 0.0108), location of tumor to middle part of kidney (P = 0.0112), postoperative highest lactase dehydrogenase (P < 0.0001), postoperative body temperature (P = 0.0314) and postoperative acute kidney injury (P < 0.0001) were significantly different between patients with a decrease in estimated glomerular filtration rate of >25% and those with a decrease in estimated glomerular filtration rate ≤25% on univariate analysis. Multivariate analysis showed that postoperative highest lactase dehydrogenase (P = 0.0408) and acute kidney injury (P = 0.000...Continue Reading

References

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Citations

Apr 3, 2014·Nephro-urology Monthly·Giacomo CaddeoNicholas M Selby
Jan 28, 2017·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Piotr ZapalaPiotr Radziszewski
May 10, 2017·The Cochrane Database of Systematic Reviews·Frank KunathNils Kroeger
Sep 27, 2018·International Journal of Urology : Official Journal of the Japanese Urological Association·Naoko KawamuraYasuhisa Fujii

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