Predictors for short-term outcomes of patients undergoing transcatheter mitral valve interventions: analysis of 778 prospective patients from the German TRAMI registry focusing on baseline renal function

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Robert SchuelerChristoph Hammerstingl

Abstract

Factors predicting outcomes after MitraClip implantation are not well defined. We aimed to report the influence of baseline renal function on short-term outcomes of patients enrolled in the investigator-initiated German transcatheter mitral valve interventions (TRAMI) registry. Twenty participating German centres prospectively included 778 patients (mean age 76.0 years [71-81], 38.8% female gender) at high surgical risk (mean logistic EuroSCORE 20% [12-32%]) undergoing TMVR with the MitraClip for the treatment of symptomatic functional (70%) or degenerative (30%) mitral valve regurgitation (FMR, DMR). The patients were stratified according to renal function before clip implantation. The prevalence of moderate to severe renal impairment (glomerular filtration rate [GFR] <60 ml/min) was 62.7% (37.3%, normal renal function [GFR >60 ml/min]; 49.6%, moderate renal impairment [GFR 30-60 ml/min]; 13.1%, severe renal impairment [GFR <30 ml/min]). TMVR was successfully completed in 98.2% of cases; acute procedural failure, in-hospital and 30-day mortality rates were 1.8%, 2.3% and 4.4%, respectively. Acute procedural failure and mortality rates (in-hospital, 30-day) were significantly higher in patients with severe renal impairment (5.9...Continue Reading

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Citations

Oct 19, 2016·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Carsten SchwenckeJoachim Schofer
Aug 9, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christos IliadisRoman Pfister
Oct 18, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Maximilian SpiekerRalf Westenfeld
Jun 25, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nicolas WernerUNKNOWN German Transcatheter Mitral Valve Intervention (TRAMI) investigators
Feb 15, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Maria Isabel KörberVolker Rudolph
May 18, 2018·Current Cardiology Reports·Matteo SaccocciFrancesco Maisano
Oct 20, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Darren Mylotte
Sep 25, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Khalid SawalhaAbdul Moiz Hafiz
Apr 4, 2017·Journal of Interventional Cardiology·Mathias OrbanJörg Hausleiter
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Nov 4, 2020·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Prasham DaveWael Abuzeid

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