Predictors of 6-month poor clinical outcomes after transcatheter aortic valve implantation

Archives of Cardiovascular Diseases
Vincent AuffretHervé Le Breton

Abstract

Patient selection for transcatheter aortic valve implantation (TAVI) remains a major concern. Indeed, despite promising results, it is still unclear which patients are most and least likely to benefit from this procedure. To identify predictors of 6-month poor clinical outcomes after TAVI. Patients who were discharged from our institution with a transcatheter-implanted aortic valve were followed prospectively. Our population was divided into two groups ('good outcomes' and 'poor outcomes') according to occurrence of primary endpoint (composite of all-cause mortality, all stroke, hospitalizations for valve-related symptoms or worsening heart failure from discharge to 6 months or 6-month New York Heart Association functional class III or IV). Patient characteristics were studied to find predictors of poor outcomes. We included 163 patients (mean age, 79.9 ± 8.8 years; 90 men [55%]; mean logistic EuroSCORE, 18.4 ± 11.4%). The primary endpoint occurred in 49 patients (mean age, 83 ± 5 years; 31 men [63%]). By multivariable analysis, atrial fibrillation (odds ratio [OR] 3.94), systolic pulmonary artery pressure ≥60 mmHg (OR 7.56) and right ventricular dysfunction (OR 3.55) were independent predictors of poor outcomes, whereas baseli...Continue Reading

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Citations

Sep 14, 2014·Progress in Cardiovascular Diseases·Matthew Finn, Philip Green
Oct 20, 2015·Expert Review of Cardiovascular Therapy·Crochan J O'Sullivan, Peter Wenaweser
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Feb 20, 2019·The American Journal of Cardiology·Mathurin BeveJean-Philippe Verhoye

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