Predictors of Abnormal Neuroimaging of the Brain in Children With Epilepsy Aged 1 Month to 2 Years: Useful Clues in a Resource-Limited Setting

Journal of Child Neurology
Oranee SanmaneechaiSurachai Likasitwattanakul

Abstract

Neuroimaging should be performed on infants with seizure. However, there are economic limitations in performing neuroimaging in a resource-limited setting. The younger the age, the higher the risk of having abnormal neuroimaging. The aim was to determine frequency and predictors of abnormal neuroimaging in children with epilepsy aged 1 month to 2 years. History, physical examination, electroencephalogram (EEG), and neuroimaging were reviewed. Thirty-seven of 49 (76%) had neuroimaging studies; 19 computed tomography (CT), 14 magnetic resonance imaging (MRI), and 4 had both. Abnormal neuroimaging was found in 19 (51%). Predictors of abnormal neuroimages are developmental delay, abnormal head circumference, and abnormal neurologic examination. Eight children (21%) had lesions on neuroimaging studies that altered or influenced management. Of 8 patients with normal examination and EEG, 1 had a brain tumor and another had arteriovenous malformation. Neuroimaging should be considered as an essential aid in the evaluation of infants with epilepsy, even in a resource-limited setting.

References

Oct 15, 1994·BMJ : British Medical Journal·R A Schoenenberger, S M Heim
Jan 1, 1994·European Neurology·E W Radue, G Scollo-Lavizzari
Apr 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·J GibbsB A Acomb
Jan 16, 2003·Seminars in Neurology·Ruben I Kuzniecky, Robert C Knowlton
Feb 22, 2008·Epilepsia·Peter Camfield, Carol Camfield
Feb 22, 2008·Epilepsia·Samuel WiebeMichelle Shapiro
Jan 13, 2010·Neurology·D T HsiehW D Gaillard
Dec 21, 2012·Epilepsia·Christin M EltzeJ Helen Cross
Apr 16, 2014·Epilepsia·Robert S FisherSamuel Wiebe

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