Predictors of atrial fibrillation early recurrence following cryoballoon ablation of pulmonary veins using statistical assessment and machine learning algorithms

Heart and Vessels
Jan BudzianowskiKatarzyna Korybalska

Abstract

Inflammation, oxidative stress, myocardial injury biomarkers and clinical parameters (longer AF duration, left atrial enlargement, the metabolic syndrome) are factors commonly related to AF recurrence. This study aims to assess the predictive value of laboratory and clinical parameters responsible for early recurrence of atrial fibrillation (ERAF) following cryoballoon ablation (CBA) using statistical assessment and machine learning algorithms. This study group comprised 118 consecutive patients (mean age, 62.5 ± 7.8 years; women 36%) with paroxysmal (54.1%) and persistent (45.9%) AF who underwent their first pulmonary vein isolation (PVI) performed by CBA (Arctic Front Advance 2nd generation 28 mm). The biomarker concentrations were measured at baseline and after CBA in a 24-h follow-up. ERAF was defined as at least a 30-s episode of arrhythmia registered by a 24 h-Holter monitor within the 3 months following the procedure. 56 clinical, laboratory and procedural variables were collected from each patient. We used two classification algorithms: support vector machines, gradient boosted tree. The synthetic minority over-sampling technique (SMOTE) was used to provide a balanced training data set. Within a period of 3 months 21 pa...Continue Reading

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Citations

Jun 13, 2019·Cardiovascular Diabetology·Quincy A HathawayJohn M Hollander
Oct 3, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giuseppe StabileClaudio Tondo
Jul 30, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Matthias Daniel ZinkUlrich Schotten
Jan 30, 2021·American Journal of Physiology. Heart and Circulatory Physiology·Ana María Sánchez de la NavaFrancisco Fernández-Avilés
Feb 19, 2021·Circulation Research·Natalia A TrayanovaJulie K Shade
Jul 3, 2021·Journal of Clinical Medicine·Jan BudzianowskiKatarzyna Korybalska
Dec 9, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Natasja M S de GrootUNKNOWN ESC Scientific Document Group

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Methods Mentioned

BETA
sedation

Software Mentioned

STATISTICA
ALARMc
ML

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