PMID: 4020124Apr 1, 1985Paper

Predictors of cardiovascular morbidity in treated hypertension: results from the primary preventive trial in Göteborg, Sweden

Journal of Hypertension
O SamuelssonG Berglund


Prognostic factors for cardiovascular disease (CVD) were studied in treated, middle-aged male hypertensives, derived from a random population sample and followed for more than 10 years. In multivariate analysis diastolic blood pressure, smoking, serum cholesterol, proteinuria, angina pectoris and previous stroke were found to be independent predictors of CVD morbidity (non-fatal myocardial infarction (MI), non-fatal stroke, or CVD death). Multivariate analyses for coronary heart disease (CHD), stroke and CVD mortality were also performed and the results are given. Life-table analyses showed a three times higher CVD incidence among smokers than amongst non-smokers and a doubled incidence for subjects with a serum cholesterol in the highest quartile, i.e. above 7.3 mmol/l, compared with those with levels below, and a three times higher incidence for subjects with proteinuria than those without. Non-smokers with a serum cholesterol below 7.3 mmol/l and free of any hypertensive organ manifestation at entry did not differ significantly in CVD morbidity from a normotensive comparison group that was derived from the same population sample. These findings in a well-defined population sample show that in spite of treatment for hypertens...Continue Reading


Dec 1, 1996·Pharmacy World & Science : PWS·R T GansevoortP E de Jong
Aug 7, 1999·The American Journal of Cardiology·A Zanchetti
May 2, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Wendy L St PeterWilliam M McClellan
May 24, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yon Su KimByung-Hee Oh
Aug 24, 1999·Current Opinion in Nephrology and Hypertension·A MimranG Du Cailar
Feb 1, 1993·Journal of Internal Medicine·U LindbladJ Ranstam
Mar 1, 1988·Clinical and Experimental Pharmacology & Physiology·J L ReidH L Elliott
Apr 11, 1992·BMJ : British Medical Journal·T HednerB E Wiholm
Jul 20, 2005·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ken OkuboTakao Saruta
Jan 29, 2011·Diabetes·Christian OttRoland E Schmieder
Jan 1, 1990·Clinical and Experimental Hypertension. Part A, Theory and Practice·L Wilhelmsen
Oct 8, 2011·Clinical and Experimental Hypertension : CHE·Hüseyin AksoyOnur Akpınar
May 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·V M CampeseR Bigazzi
Oct 16, 2004·Kidney International. Supplement·Dick de Zeeuw
Oct 16, 2004·Kidney International. Supplement·Julian SeguraLuis M Ruilope
May 1, 1991·The American Journal of Cardiology·G P VyssoulisP K Toutouzas
May 18, 2004·Journal of the American College of Cardiology·Giuseppe SchillaciElmo Mannarino
Aug 1, 1995·Kidney International·E S StroesT J Rabelink
Mar 1, 1993·Scandinavian Journal of Social Medicine·U LindbladM Peterson
May 1, 1990·Hypertension·B L KasiskeW F Keane
Oct 20, 2004·Circulation·Folkert W AsselbergsUNKNOWN Prevention of Renal and Vascular Endstage Disease Intervention Trial (PREVEND IT) Investigators
Oct 3, 2002·Journal of Hypertension·Lars WeinehallLars H Lindholm
Jun 30, 2009·Current Opinion in Nephrology and Hypertension·Rigas G Kalaitzidis, George L Bakris
Jul 11, 2006·Journal of the American Society of Nephrology : JASN·Coen D A Stehouwer, Yvo M Smulders
Jul 23, 2003·Journal of Human Hypertension·C CuspidiUNKNOWN Lombardy Regional Section of the Italian Society of Hypertension

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.