Predictors of exercise capacity following exercise-based rehabilitation in patients with coronary heart disease and heart failure: A meta-regression analysis

European Journal of Preventive Cardiology
Jamal UddinRod S Taylor

Abstract

The aim of this study was to undertake a comprehensive assessment of the patient, intervention and trial-level factors that may predict exercise capacity following exercise-based rehabilitation in patients with coronary heart disease and heart failure. Meta-analysis and meta-regression analysis. Randomized controlled trials of exercise-based rehabilitation were identified from three published systematic reviews. Exercise capacity was pooled across trials using random effects meta-analysis, and meta-regression used to examine the association between exercise capacity and a range of patient (e.g. age), intervention (e.g. exercise frequency) and trial (e.g. risk of bias) factors. 55 trials (61 exercise-control comparisons, 7553 patients) were included. Following exercise-based rehabilitation compared to control, overall exercise capacity was on average 0.95 (95% CI: 0.76-1.41) standard deviation units higher, and in trials reporting maximum oxygen uptake (VO2max) was 3.3 ml/kg.min(-1) (95% CI: 2.6-4.0) higher. There was evidence of a high level of statistical heterogeneity across trials (I(2) statistic > 50%). In multivariable meta-regression analysis, only exercise intervention intensity was found to be significantly associated w...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Mar 15, 2002·The New England Journal of Medicine·Jonathan MyersJ Edwin Atwood
Jun 30, 2006·Contemporary Clinical Trials·Rebecca DerSimonian, Raghu Kacker
Dec 17, 2009·Journal of Science and Medicine in Sport·Kevin NortonDaryl Sadgrove
Jan 8, 2010·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Rita Hwang, Thomas Marwick
Jan 21, 2010·BMJ : British Medical Journal·Hasnain M DalalRod S Taylor
May 25, 2010·Scandinavian Journal of Medicine & Science in Sports·H ValkeinenU M Kujala
Oct 20, 2010·Circulation·Peter Kokkinos, Jonathan Myers
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
May 2, 2012·Psychological Methods·Ken Kelley, Kristopher J Preacher
Sep 19, 2012·European Journal of Preventive Cardiology·Suzan van der MeerJob van der Palen
Jun 12, 2013·Journal of the American College of Cardiology·Clyde W YancyUNKNOWN American Heart Association Task Force on Practice Guidelines
May 9, 2014·International Journal of Cardiology·Rod S TaylorUNKNOWN ExTraMATCH II Collaborators
Oct 13, 2014·Heart, Lung & Circulation·Adrian D ElliottEdoardo C Aromataris
Nov 30, 2014·Heart Failure Clinics·Jonathan MyersRod S Taylor

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Citations

Oct 4, 2016·The Canadian Journal of Cardiology·Mark J HaykowskyDalane W Kitzman
Jul 22, 2016·International Journal of Cardiology·Ann-Dorthe ZwislerRod S Taylor
Dec 14, 2016·European Journal of Preventive Cardiology·Renata L BonaNadine Oliveira Clausel
Apr 8, 2017·European Journal of Preventive Cardiology·Stamatios Adamopoulos, Constantinos H Davos
Apr 8, 2017·Progress in Cardiovascular Diseases·Trine KarlsenØivind Rognmo
Sep 25, 2017·Medicine and Science in Sports and Exercise·Esmée A BakkerThijs M H Eijsvogels
Jan 5, 2018·European Heart Journal·Petra Zubin MaslovJagat Narula
Jul 25, 2018·European Journal of Preventive Cardiology·Alf I Larsen
Sep 25, 2018·European Journal of Preventive Cardiology·Erik H Van ItersonThomas P Olson
Apr 30, 2019·Scandinavian Journal of Medicine & Science in Sports·Ann Christin Helgesen BjørkeSveinung Berntsen
Apr 5, 2018·The Journal of Cardiovascular Surgery·Fredrike BlokzijlIwan C van der Horst
Dec 31, 2019·ESC Heart Failure·Markus S AnkerWilhelm Haverkamp
Aug 3, 2019·Journal of the Saudi Heart Association·Waleed AlHabeebWalid Hassan
Nov 13, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Jamal UddinAnn-Dorthe Zwisler
Sep 27, 2019·MMW Fortschritte der Medizin·Marthin KaroffBirna Bjarnason-Wehrens
Nov 30, 2018·Journal of Cardiopulmonary Rehabilitation and Prevention·Nicolai MikkelsenEva Prescott
Feb 23, 2020·European Journal of Preventive Cardiology·Jari A Laukkanen
Jun 11, 2019·European Journal of Preventive Cardiology·Birna Bjarnason-WehrensUNKNOWN German Society of Cardiovascular Prevention and Rehabilitation (DGPR)
Jun 27, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Yong Gon SeoJi Dong Sung
Jan 11, 2020·Journal of Sport and Health Science·Shanshan GuoTiemin Liu
Jan 20, 2021·International Journal of Psychiatry in Medicine·Christopher M CelanoJeff C Huffman
Nov 2, 2020·Patient Education and Counseling·Tuğba Karataş, Ülkü Polat
Jun 3, 2021·Journal of Clinical Medicine·Bernhard Rauch On Behalf Of The Cardiac Rehabilitation Guideline Group
Sep 19, 2020·Journal of Cardiopulmonary Rehabilitation and Prevention·Dion CandelariaRobyn Gallagher
Mar 30, 2019·Journal of the American College of Cardiology·Rod S TaylorUNKNOWN ExTraMATCH II Collaboration
Aug 24, 2021·Frontiers in Cardiovascular Medicine·Andrea PassantinoMaria Teresa La Rovere
Sep 18, 2021·Nature Reviews. Cardiology·Rod S TaylorSinéad T J McDonagh

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Software Mentioned

ExTraMATCH
Cochrane
STATA
Review Manager

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