Predictors of favorable outcome after mechanical thrombectomy for anterior circulation acute ischemic stroke in octogenarians

Journal of Neuroradiology. Journal De Neuroradiologie
Matthias BarralMichel Piotin

Abstract

Mechanical thrombectomy for anterior circulation large vessel occlusion (LVO) improves functional outcome at three months. This therapeutic approach is the new gold standard, with a benefit being also observed in elderly patients. However, data are limited in this heterogeneous and fragile population. The objectives of this study were, first, to describe outcome after mechanical thrombectomy in a representative group of patients over 80. Second, to evaluate factors associated with a favorable functional outcome after thrombectomy for anterior circulation LVO in elderly patients (aged≥80 years). A total of 169 patients with anterior circulation LVO referred for an endovascular treatment were included. Primary outcome evaluated functional outcome at three months. Multivariable analysis was performed to identify prognostic factors in elderly patients with pre-stroke mRS≤3. Overall, 25.34% of patients (43/169) were functionally independent at three months (mRS≤2) and 16.57% (28/169) had a moderate functional disability (mRS=3). Mortality rate was 33.14% (56/169). At 24h, 7.1% of patients (12/169) had symptomatic hemorrhage. Male gender (P=0.033), low initial NIHSS (P=0.037), higher DWI-ASPECTS (P=0.022) and use of intravenous throm...Continue Reading

Citations

Feb 25, 2020·Journal of the American Heart Association·Lukas MeyerUNKNOWN German Stroke Registry–Endovascular Treatment (GSR‐ET) †
Aug 12, 2019·Journal of Neurointerventional Surgery·Federico CagnazzoVincent Costalat
Feb 4, 2019·Journal of Neurointerventional Surgery·Ali AlawiehAlejandro Spiotta
Apr 29, 2019·Journal of Neurointerventional Surgery·Lukas MeyerPanagiotis Papanagiotou
Jan 11, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Younsu AhnWoong Yoon
May 16, 2019·Diabetology & Metabolic Syndrome·Thomas I NathanielJordan Gainey
Oct 21, 2020·Journal of Neurointerventional Surgery·Julien AllardBenjamin Maïer
Oct 15, 2019·Journal of Neuroradiology. Journal De Neuroradiologie·Grégoire Boulouis, Robert Fahed
Sep 11, 2020·Journal of Neuroradiology. Journal De Neuroradiologie·Mahmoud ElhoranyFrédéric Clarençon
Dec 31, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Yen-Jun LaiChih-Wei Tang

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