Predictors of gastroesophageal reflux symptoms in pregnant women screened for sleep disordered breathing: a secondary analysis

Clinics and Research in Hepatology and Gastroenterology
Fadlallah HabrGhada Bourjeily

Abstract

Gastroesophageal reflux disease (GERD) is common in pregnancy. The cause is multifactorial, including a decreased or transient lower esophageal sphincter relaxation, increased intra-abdominal pressure, and gastrointestinal motility disturbances. Evaluate the incidence of GERD in pregnancy and assess predictors and predisposing factors. This is a secondary analysis of a survey of postpartum women regarding symptoms of sleep disordered breathing (SDB) and GERD performed at a large tertiary care center. Patients rated heartburn frequency during pregnancy as either never, occasionally/sometimes, or frequently/always. Pregnancy outcomes and newborn information was collected. Categorical variables were compared by Fisher's exact test and continuous variables were compared by Anova or Kruskal-Wallis test. Multinominal logistic regression was also performed. Information regarding 1000 mothers and 1025 newborns was reviewed. The majority of mothers were Caucasian (68.8%) with mean age 29 ± 6.1 years. A total of 56.7% had GERD frequently/always; and 25.5% had none. GERD symptoms correlated with pre-pregnancy body mass index (BMI), BMI at delivery, maternal age, smoking and symptoms of SDB. There was no significant correlation between fet...Continue Reading

References

Apr 1, 1977·Anaesthesia·V M HeyD S Sharp
Sep 1, 1992·British Journal of Obstetrics and Gynaecology·J M MarreroJ D Maxwell
Apr 1, 1967·Anaesthesia·A A SpenceW E Finlay
Mar 1, 1994·Journal of Psychosomatic Obstetrics and Gynaecology·S SuzukiE Satohisa
Dec 3, 1998·Journal of Gastroenterology and Hepatology·K Y HoO A Viegas
Apr 25, 2000·Obstetrics and Gynecology·G D CoronadoS M Schwartz
Mar 15, 2003·Gastroenterology Clinics of North America·Joel E Richter
Aug 3, 2005·Annals of Internal Medicine·Howard HampelHashem B El-Serag
Oct 18, 2005·Alimentary Pharmacology & Therapeutics·J E Richter
Jun 2, 2006·The New England Journal of Medicine·Brian C JacobsonCarlos A Camargo
Mar 27, 2009·Digestion·Sara Fill MalfertheinerSerban-Dan Costa
Oct 8, 2009·Current Opinion in Obstetrics & Gynecology·Kathleen M RasmussenAnn L Yaktine
Jun 8, 2010·The European Respiratory Journal·G BourjeilyM A Miller

❮ Previous
Next ❯

Citations

Aug 9, 2012·Sleep & Breathing = Schlaf & Atmung·Ghada BourjeilyMargaret Miller
Aug 14, 2012·BMC Pregnancy and Childbirth·Mirjam LukasseBerit Schei
Feb 20, 2013·Sleep & Breathing = Schlaf & Atmung·Ghada BourjeilyMariam Louis
Aug 27, 2014·Clinics in Chest Medicine·Dennis OyiengoGhada Bourjeily
Apr 13, 2018·Anesthesia and Analgesia·Jennifer E DominguezAshraf S Habib
Apr 29, 2015·Current Opinion in Anaesthesiology·Vinod PatilDhuleep S Wijayatilake
Jun 8, 2017·Journal of Clinical Gastroenterology·Richard HuntUNKNOWN Review Team:
Jun 4, 2021·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·I M MadaevaL I Kolesnikova

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
Bhavadharini RamuVenkataraman Jayanthi
European Journal of Obstetrics, Gynecology, and Reproductive Biology
Saleh Mohsen Al-Amri
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Hashem B El-SeragMark A Gilger
© 2021 Meta ULC. All rights reserved